research The blastema and epimorphic regeneration in mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
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research Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment
Finasteride affects prostate weights and pituitary activity differently with age.
research Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia
AMT may cause hair loss and changing dWAT activity could help treat it.
research A Note on Postinflammatory Hair Darkening
Hair can darken after inflammation and then return to its original color.
research A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines
Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.
research Hutchinson-Gilford progeria syndrome - A brief introduction
Hutchinson-Gilford Progeria Syndrome caused rapid aging due to a genetic mutation, with treatments to manage symptoms.
research Regard the end: Harnessing physiology to provide better understanding of the mechanisms underpinning frailty
Understanding how different body systems interact can improve how we prevent or treat frailty in aging.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Fibroblast‐derived growth factors and exosomes as cosmeceuticals
Fibroblast-derived growth factors and exosomes can significantly improve skin aging.
research The effects of infrared radiation on the human skin
Infrared radiation can cause skin aging and cancer at high temperatures but may have therapeutic benefits at controlled levels.
research Evaluation of the Efficacy of Intense Pulsed Light in Skin Rejuvenation
Intense Pulsed Light treatments significantly improve signs of aging and sun damage on the skin.
research International Briefs
Australia improved medical education and Canada focused on professionalism and patient safety.
research Inhibition of TNF-α-Induced Collagen Degradation and Oxidative Damage by Centipeda minima and Brevilin A in Human Dermal Fibroblasts
Centipeda minima and brevilin A protect skin cells from damage and aging.
research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
research Contents
Men's facial rejuvenation involves unique challenges and is increasingly popular, with many opting for nonsurgical treatments.
research Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
research The JAK/STAT signaling pathway: from bench to clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Melasma, a photoaging disorder
Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
research Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation
Stem cell vesicles can reduce skin aging from UVB by lowering inflammation and oxidative stress.
research Stimulation of Hair Growth by Small Molecules that Activate Autophagy
Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
research Chronic graft versus host disease and skin
cGVHD often severely affects the skin, causing rapid aging and other issues.
research Hair and nail diseases in the mature patient
Older adults commonly experience hair loss and nail disorders due to aging and health changes, affecting their quality of life.
research Implication of microRNA regulation in para-phenylenediamine-induced cell death and senescence in normal human hair dermal papilla cells
Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Keratin
Understanding how keratin structures in hair are arranged and interact is key for creating methods to extract and purify them.
research Extracellular vesicle-derived lncRNA VIM-AS1 promotes diabetic wound healing by promoting glycolysis and alleviating cellular senescence
lncRNA VIM-AS1 helps heal diabetic wounds by boosting energy production and reducing cell aging.
research Clinical Efficacy of Topical or Oral Soy Supplementation in Dermatology: A Systematic Review
Soy supplements improve various skin conditions and aging signs, with topical use boosting skin barrier function.
research TLR2 regulates hair follicle cycle and regeneration via BMP signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research Author response: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
Moles may stop growing because of cell cooperation, not just because of aging cells.
research Decision letter: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
Moles may stop growing due to cell cooperation, not just because of individual cell aging.