March 2025 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” Baricitinib effectively improved skin and hair conditions in a patient with alopecia areata and atopic dermatitis.
January 2025 in “Indian Journal of Dermatology” Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.
November 2023 in “Journal of Investigative Dermatology” Highly active but fewer CD14+CD16- monocytes are found in Alopecia Areata patients, regardless of severity.
277 citations
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December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
238 citations
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April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
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December 2017 in “Trends in immunology” Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
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May 2022 in “Journal of Advanced Research” Enhancing glycolysis in mesenchymal stromal/stem cells boosts their immune functions and therapy potential.
51 citations
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March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.
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August 2022 in “Frontiers in Immunology” Psoriasis involves an imbalance between certain immune cells, and targeting these could help restore skin health.
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April 2021 in “JAMA Network Open” Higher variability in systolic blood pressure increases long-term mortality risk in coronary artery disease patients.
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January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
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May 2023 in “International Journal of Preventive Medicine” Long COVID causes lasting symptoms and needs vaccines for prevention and a team approach for treatment.
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November 2023 in “Applied Materials Today” Nanoemulsions can effectively treat skin cancer with fewer side effects.
34 citations
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November 2022 in “Clinical and Experimental Dermatology” People with alopecia areata are more likely to have other immune-related conditions.
32 citations
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August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
29 citations
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January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
28 citations
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August 2020 in “F1000Research” Better understanding and new treatments for hidradenitis suppurativa are emerging, but more research is needed.
27 citations
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February 2023 in “Frontiers in Cell and Developmental Biology” WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
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October 2020 in “Biomedicines” Bioengineered skin models help reduce animal testing and advance research in cosmetics and skin disease.
24 citations
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March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
20 citations
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February 2023 in “Biology” Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
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November 2019 in “International Journal of Environmental Research and Public Health” Breathing in high levels of certain air pollutants significantly increases women's risk of developing Polycystic Ovary Syndrome.
18 citations
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September 2023 in “Experimental Dermatology” The skin microbiome plays a key role in treating atopic dermatitis.
18 citations
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February 2023 in “eLife” ILC1-like cells can independently cause alopecia areata.
16 citations
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April 2024 in “Proceedings of the National Academy of Sciences” HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.
14 citations
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September 2021 in “International journal of molecular sciences” Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
12 citations
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January 2018 in “Pharmacology & pharmacy” Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.
10 citations
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January 2023 in “Journal of the European Academy of Dermatology and Venereology” Alopecia areata greatly affects people's life quality, mental health, and work life.
10 citations
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July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
10 citations
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January 2017 in “Dermato-Endocrinology” Scarring folliculitis type of acne inversa is linked to specific symptoms and lifestyle factors like smoking and being overweight.