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Association of Psoriasis and Psoriatic Arthritis with Human Leukocyte Antigen and Killer Cell Immunoglobulin-Like Receptor Gene Frequency: A Multiethnic Population Study

research Association of psoriasis and psoriatic arthritis with human leukocyte antigen and killer cell immunoglobulin–like receptor gene frequency: A multiethnic population study

February 2009 in “Journal of The American Academy of Dermatology”

Certain immune system genes are linked to a higher risk of psoriasis and psoriatic arthritis, while others may offer protection.

research Four murine monoclonal antibodies specific for the inner root sheath in the human hair follicle

1 citations , January 1989

Four antibodies were developed to help study hair follicle cell differentiation.

research Weeping Wound, Disgruntled Gut and Fading Hunger: Acrodermatitis Enteropathica in an Infant

December 2025 in “Cureus”

Zinc supplements effectively treat inherited zinc deficiency in infants.

Clinical Findings, Response to Steroid Treatment, and Recurrence Rate in Alopecia Areata Patients With or Without a Nonsynonymous Variant of Coiled-Coil Alpha-Helical Rod Protein 1

research Clinical Findings, Response to Steroid Treatment, and Recurrence Rate in Alopecia Areata Patients with or without a Nonsynonymous Variant of Coiled-Coil Alpha-Helical Rod Protein 1

January 2023 in “Annals of Dermatology”

Patients with a specific genetic variant have more severe alopecia areata and higher recurrence rates.

research POLYCOMB REPRESSIVE COMPLEX 1 IS REQUIRED TO MAINTAIN STEM CELL IDENTITY AND TO PRESERVE ADULT TISSUE HOMEOSTASIS.

January 2020 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)”

Polycomb Repressive Complex 1 is crucial for keeping stem cells stable and maintaining healthy adult tissues.

research Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity

7 citations , January 2023 in “Frontiers in cell and developmental biology”

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

research JAK Family Expression and Therapeutic Implications in Primary Cicatricial Alopecias

October 2025 in “International Journal of Dermatology”

JAK inhibitors may help treat certain types of hair loss, but more research is needed.

research A novel point mutation of keratin 17 (KRT17) in a Japanese family with pachyonychia congenita type 2: an RNA-based genetic analysis using a single hair bulb

5 citations , June 2008 in “British Journal of Dermatology”

Inhibition of the Mitochondrial Pyruvate Carrier Promotes ATF4-Dependent Stress Responsive Metabolic Rewiring and Cell Cycle Arrest in the Human Hair Follicle

research 1367 Inhibition of the mitochondrial pyruvate carrier promotes ATF4–dependent stress responsive metabolic rewiring and cell cycle arrest in the human hair follicle

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.

research A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions

47 citations , April 2000 in “Experimental Dermatology”

A new gene mutation causes a rare type of hair loss.

research BH14 Irish dermatologists’ experience with Janus kinase inhibitors in alopecia areata

June 2025 in “British Journal of Dermatology”

Irish dermatologists urgently need guidelines for using JAK inhibitors in treating alopecia areata.

research The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research^*

88 citations , July 2009 in “Experimental and Clinical Endocrinology & Diabetes”

research BH17 Bridging the gap: identifying dual-targeting therapies for patients with alopecia areata and coexisting immune-mediated inflammatory diseases

June 2025 in “British Journal of Dermatology”

Dual-targeting therapies like Janus kinase inhibitors may treat both alopecia areata and other immune diseases.

Association of Rs231775 Genetic Variant of Cytotoxic T-Lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case-Control Study

research Association of Rs231775 Genetic Variant of Cytotoxic T-lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case–Control Study

7 citations , July 2020 in “Immunological Investigations”

The rs231775 genetic variant is linked to a higher risk and severity of Alopecia Areata in males.

research Progressive alopecia areata during TNF-α inhibition with intralesional corticosteroid failure and subsequent improvement following JAK1 inhibition

1 citations , May 2026 in “Journal of Dermatological Treatment”

A 55-year-old woman with seropositive rheumatoid arthritis developed progressive alopecia areata (AA) while on golimumab and leflunomide treatment, despite well-controlled arthritis. Her alopecia worsened over 14 months with intralesional corticosteroid treatment, as indicated by an increase in her Severity of Alopecia Tool (SALT) score from 20 to 50. Upon switching to the JAK1 inhibitor upadacitinib, her hair regrowth began within six weeks, and her SALT score improved to 15 by three months. This case suggests that JAK1 inhibition may be an effective treatment for AA that develops during TNF-α inhibitor therapy, although spontaneous remission and delayed effects of corticosteroids cannot be ruled out.

research Novel KRT83 and KRT86 mutations associated with monilethrix

18 citations , January 2015 in “Experimental Dermatology”

New mutations in KRT83 and KRT86 are linked to the hair disorder monilethrix.

research Plant growth and phosphorus accumulation of wild type and two root hair mutants of Arabidopsis thaliana (Brassicaceae)

183 citations , July 2000 in “American Journal of Botany”

Root hairs help Arabidopsis plants absorb more phosphorus when it's scarce.

research Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

65 citations , November 2013 in “The EMBO Journal”

HDAC1 is crucial for skin development and preventing tumors.

research Identification of the Ovine Keratin-Associated Protein 21-1 Gene and Its Association with Variation in Wool Traits

7 citations , July 2019 in “Animals”

The KRTAP21-1 gene affects wool yield and can help improve wool production.

research Case report: Acrodermatitis enteropathica result from a novel SLC39A4 gene mutation

November 2022 in “Frontiers in pediatrics”

A girl with skin rashes and low zinc levels improved with zinc supplements and had new gene mutations linked to her condition.

research Role of the ACTH/MC2R System in the Hair Cycle in Mice

1 citations , January 2016 in “Journal of Biosciences and Medicines”

The ACTH/MC2R system is crucial for controlling hair growth cycles in mice.

research Variant 1859G→A (Arg620Gln) of the “Hairless” Gene: Absence of Association with Papular Atrichia or Androgenetic Alopecia

14 citations , July 2001 in “American Journal of Human Genetics”

Haplogroup X found in Altaian population supports Amerindian origin.

research Analyse de la régulation du gène Hairless et identification des voies de signalisation affectées chez les mutants «bald Mill Hill».

January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)”

The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.

research The biphasic regulatory effect of diphencyprone on mouse hair growth and its relation to protein kinase C isoforms

March 1998 in “Journal of dermatological science”

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

research Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain during Epidermal Differentiation

25 citations , October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.

research Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists

November 2015 in “Journal of the Korea Academia-Industrial cooperation Society”

The new assay can help develop products for hair re-growth.

research Polymorphism of keratin-associated protein (KAP) 7 gene and its association with wool traits in Rambouillet sheep

3 citations , May 2018 in “The Indian Journal of Animal Sciences”

The KAP 7 gene affects wool traits in Rambouillet sheep, with the BB genotype showing the best wool characteristics.

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