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Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

SHBG may be a useful early indicator and treatment target for PCOS.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Iron deficiency may contribute to hair loss.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

Eating isoflavone can help mice grow hair by increasing a growth factor.

Low prolactin in young women may increase heart and metabolism risks.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Protein-losing enteropathy worsened with lupus symptoms but improved with prednisolone.

Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Sonicated platelet-rich plasma boosts hair growth by activating stem cells.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

Copper and iron cause keratin damage in hair by converting methionine to homocysteine.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

t-Flavanone may help hair growth by reducing a specific protein's activity in skin cells.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

DHT affects testicular development and regulates spermatogenesis in some fish.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

Activin A is important for creating new hair follicles.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.