34 citations
,
December 2015 in “Neuroscience & Biobehavioral Reviews” Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
34 citations
,
June 2014 in “The BMJ” Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.
34 citations
,
April 2007 in “Neuroscience” Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
33 citations
,
April 2002 in “Journal of Cutaneous Medicine and Surgery” Eating disorders can cause skin problems that need treating the underlying condition for better health.
32 citations
,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
30 citations
,
November 2018 in “Fertility and Sterility” Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.
30 citations
,
April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
30 citations
,
November 2000 in “British Journal of Cancer” Reduced sexual drive may be linked to male breast cancer, while anti-estrogenic factors might lower the risk.
29 citations
,
June 2017 in “Journal of Inherited Metabolic Disease” High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
26 citations
,
October 2018 in “British Journal of Dermatology” Regular use of sunscreen may be linked to frontal fibrosing alopecia.
26 citations
,
February 2002 in “Urologic clinics of North America” The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.
25 citations
,
July 2014 in “Hong Kong medical journal” Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.
25 citations
,
May 2014 in “Facial Plastic Surgery” PRFM may help treat hair loss, especially in mild cases.
25 citations
,
December 2018 in “Human Molecular Genetics” The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
25 citations
,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
24 citations
,
June 2011 in “International Journal of Dermatology” Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.
23 citations
,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
23 citations
,
June 2018 in “Facial Plastic Surgery” Platelet-Rich Plasma (PRP) is a low-risk treatment for Androgenic Alopecia (AGA) that generally improves hair count or density, but more research is needed for optimization.
23 citations
,
September 2016 in “BMC musculoskeletal disorders” Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.
23 citations
,
January 2007 in “Archives of Andrology” Finasteride may negatively affect male fertility.
22 citations
,
November 2018 in “Breast Cancer Research and Treatment” The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.
20 citations
,
October 2021 in “PLoS ONE” Newborn skin is uniquely prepared to adapt to new environments compared to adult skin.
20 citations
,
June 2012 in “Human Reproduction” Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.
19 citations
,
September 2016 in “Pharmacotherapy” Finasteride for hair loss increases risk of long-lasting sexual dysfunction.
18 citations
,
March 2009 in “Medical Hypotheses” The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
17 citations
,
September 2020 in “Journal of Endocrinological Investigation” Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
17 citations
,
October 2017 in “Journal of Cutaneous Medicine and Surgery” No treatment has been proven to effectively stop hair loss or regrow hair in Frontal Fibrosing Alopecia, and more research is needed.
17 citations
,
November 2012 in “Cancer Epidemiology, Biomarkers & Prevention” Early balding at 40 increases prostate cancer risk.
16 citations
,
May 2019 in “International Journal of Women's Dermatology” The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.
16 citations
,
March 2017 in “Bone Marrow Transplantation” Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.