research Pitfalls of PCR-Based Strategy for Genotyping Cre-Loxp Mice
PCR genotyping in cre-loxP mice can be inaccurate due to unintended gene deletions in non-target tissues.
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research Screening: seeking a balance
The document concludes that better training and education are needed for proper cancer screening and criticizes the GMC's inaction as harmful to clinical ethics in the UK.
research Low-energy laser in the treatment of alopecia of the scalp
Low-energy laser therapy can improve scalp alopecia treatment when combined with classical methods.
research Multicenter double blind randomized placebo controlled clinical trial of minoxidil gel in the treatment of alopecia areata
2.2% minoxidil gel effectively and safely treats alopecia areata.
research Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata over 52 Weeks of Continuous Therapy in Two Phase III Trials (BRAVE-AA1 and BRAVE-AA2)
Baricitinib improved severe hair loss in adults over 52 weeks and was safe to use.
research Drug Information Analysis Service
Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
research Terazosin or baclofen in young men with chronic orchialgia: A cohort study of 499 patients
Both terazosin and baclofen effectively reduce pain in young men with chronic testicular pain, with no difference in their effectiveness.
research A10.09 Safety data of four treatment regimens in early rheumatoid arthritis patients
All four treatments for early rheumatoid arthritis had similar and mostly mild side effects.
research Choice of recall period for patient-reported outcome (PRO) measures: criteria for consideration
Choosing the right recall period for patient feedback is important for accurate data and depends on the disease, symptom changes, and patient impact.
research Submission to the College of Physicians and Surgeons of Ontario Re: Medical Assistance in Dying
The document concludes that forcing doctors to assist in euthanasia against their will is dangerous and goes against democratic values.
research Abstract: Modified Conchal Cartilage Sandwich Graft Method for Repair of Split Ear Lobe
A new earlobe repair method using cartilage grafts showed high satisfaction and no re-splitting.
research FINASTERIDE (PLUS ORAL CONTRACEPTIVE PILL) VS METFORMIN IN TREATMENT OF POLYCYSTIC OVARY SYNDROME-RELATED INFERTILITY: A PROSPECTIVE RANDOMIZED TRIAL
research Evaluation of fractional carbon dioxide laser alone versus its combination with betamethasone valerate in treatment of alopecia areata, a clinical and dermoscopic study
The fractional carbon dioxide laser is a safe and effective treatment for alopecia areata and works better than betamethasone valerate cream alone.
research [RETRACTED] Restolin Reviews Amazon: UK, USA, Australia, South Africa, Canada, NZ (Ingredients Updates) v1
The document is retracted and cannot be summarized.
research Phase I/II randomized bilateral half-head comparison of topical bexarotene 1% gel for alopecia areata
Topical bexarotene 1% gel might help regrow hair in alopecia areata and is generally safe.
research A multi-centre, double-blind, randomised, vehicle-controlled study for a quantitative estimation of hair re-growth in male subjects with androgenetic alopecia treated over 6 month with two ethanolic PSK 3841 solutions (2.5% and 5%)
research News & Notes
Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
research Efficacy of platelet-rich plasma in Asians with androgenetic alopecia: A randomized controlled trial
research THU0301 A Phase II Trial of Retinoids on Lupus Nephritis in A Single Center
Retinoids may help treat lupus nephritis and reduce steroid use.
research Allopregnanolone mediates the exacerbation of Tourette-like responses by acute stress in mouse models
Stress worsens Tourette symptoms by increasing allopregnanolone levels.
research Recent European legal developments on second medical uses and dosage regimes
European patent law now allows patents for new uses and dosages of known drugs, but protection scope is unclear.
research Alfatradiol (0,025 %) - Eine wirksame und sichere Therapieoption zur Behandlung der androgenetischen Alopezie bei Frauen und Männern
Alfatradiol (0.025%) is an effective and safe treatment for hair loss in both women and men.
research PRP versus intralesional triamcinolone for alopecia areata comparative study
PRP is more effective than triamcinolone for treating alopecia areata.
research To study hypoactive sexual desire disorder in a fragile X carrier female successfully treated with local testosterone application
Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
research Efficacy and safety of deuruxolitinib, an oral selective Janus kinase inhibitor, in adults with alopecia areata: Results from the Phase 3 randomized, controlled trial (THRIVE-AA1)
Deuruxolitinib effectively promotes hair regrowth in adults with alopecia areata.
research ANTI-INFLAMMATORY ACTIVITY OF PLATELET-RICH PLASMA TREATMENT IN THE INFLAMMATION MANAGEMENT OF KNEE OSTEOARTHRITIS: EXPERIMENTAL STUDY
Platelet-rich plasma treatments reduce knee osteoarthritis inflammation, with pure PRP being more effective.
research A randomized, double blind, placebo controlled, split patch study to evaluate the effects of platelet rich plasma on alopecia areata
Platelet rich plasma was slightly more effective than no treatment for hair loss in alopecia areata patients.
research Re
The letter criticizes generalizations about older patients' abilities and calls for respectful, individualized care, while the original authors defend the need to adapt communication for those with impairments.
research ADVANCES IN FUNCTIONAL NEUROSURGERY – MACHINE LEARNING, NEURAL ENGINEERING AND ROBOTICS IN TREATMENT OF NEURODEGENERATIVE DISORDERS
AI and robotics are improving treatment and monitoring of neurodegenerative disorders like Parkinson's.
research Reporting on Adverse Clinical Events
Different medications can cause serious side effects in some people.