June 2020 in “Journal of skin and stem cell” The patient's hair loss from alopecia totalis returned despite initial successful treatment.
April 2020 in “Trends in Immunotherapy” Combining triamcinolone acetonide and immunotherapy can help regrow hair in some alopecia totalis patients.
Topical calcipotriol successfully treated hair loss in three patients with Alopecia Totalis.
March 2019 in “Applied sciences” Laser therapy might help regrow hair in alopecia totalis better than steroids alone.
August 2018 in “Journal of the American Academy of Dermatology” Tofacitinib is a potential alternative treatment for alopecia totalis, especially in patients with a shorter duration of the condition and more preserved hair follicles, but the overall response rate is low.
March 2018 in “Trends in Immunotherapy” Combining triamcinolone acetonide with immunotherapy can help regrow hair in some alopecia totalis patients.
January 2018 in “Springer eBooks” Alopecia totalis/universalis is a severe form of hair loss where all body hair is lost.
April 2017 in “Childhood Kidney Diseases” Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.
January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Botulinum toxin type A did not help regrow hair in severe alopecia cases.
January 2016 in “Hair therapy & transplantation” Hair UpTM effectively and safely promotes hair regrowth, especially in minors.
January 2015 in “Dermatology online journal” A man with total hair loss also developed a rare nail condition, likely due to autoimmune issues.
Higher doses of prednisone and triamcinolone acetonide successfully treated 8 out of 10 alopecia totalis patients.
14 citations
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June 2019 in “Dermatologic therapy” PRP did not significantly regrow hair in alopecia areata totalis patients.
June 2023 in “Biological & clinical sciences research journal” Combining methotrexate with low-dose prednisone is more effective for hair regrowth in alopecia areata totalis.
The patient with total hair loss did not regrow hair despite treatment, indicating a poor outlook for this type of hair loss.
105 citations
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December 1995 in “British journal of dermatology/British journal of dermatology, Supplement” PUVA treatment is generally ineffective for alopecia areata.
39 citations
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April 2003 in “Australasian journal of dermatology” PUVA treatment led to significant hair regrowth in over half of the patients with alopecia areata totalis and universalis.
16 citations
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March 2015 in “Dermatologic therapy” Zinc supplementation may be an important part of treating severe hair loss.
14 citations
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February 2021 in “Journal of the European Academy of Dermatology and Venereology” A COVID-19 patient with severe hair loss did not improve with hair loss medication after stopping and restarting it due to the infection.
5 citations
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May 2015 in “The Journal of Dermatology” Topical corticosteroids can help treat severe alopecia areata when other treatments fail.
Improving oral health may help hair regrowth in children with alopecia areata.
October 2014 in “Aktuelle Dermatologie” A 19-year-old with MRKHS developed complete hair loss, and treatment options were discussed.
2 citations
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February 2024 in “Indian Dermatology Online Journal” 3 citations
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July 2023 in “International Journal of Trichology” February 2026 in “Journal of Drugs in Dermatology” 78 citations
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July 1984 in “Journal of Investigative Dermatology”
238 citations
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November 2016 in “Journal of The American Academy of Dermatology” Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.
222 citations
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September 2016 in “JCI insight” Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.
182 citations
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December 2017 in “Journal of the American Academy of Dermatology” Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.
182 citations
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October 2003 in “British Journal of Dermatology” The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.