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research Lichenoid dermatitis from interferon alpha-2a in a patient with metastatic renal cell carcinoma and seronegative HCV

4 citations , April 2016 in “Journal of The American Academy of Dermatology”

A patient with advanced kidney cancer and no hepatitis C developed skin inflammation due to a drug called interferon alpha-2a.

Combined Oral Contraceptives Promote Androgen Receptor And Estrogen Receptor Alpha Upregulation In The Female Prostate (Skene’s Paraurethral Glands) Of Adult Gerbils (Meriones Unguiculatus)

research Combined oral contraceptives promote androgen receptor and oestrogen receptor alpha upregulation in the female prostate (Skene’s paraurethral glands) of adult gerbils (Meriones unguiculatus)

3 citations , January 2018 in “Reproduction, Fertility and Development”

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

research Hair Loss Induced by Tumor Necrosis Factor Alpha Inhibitors

2 citations , January 2014 in “Journal of clinical and investigative dermatology”

Some drugs used to treat immune conditions may cause different types of hair loss.

research Bullous Lesions at Polyethylene Glycol Interferon-alpha-2a Inoculation Site in a Hepatitis C Virus-infected Subject

2 citations , January 2007 in “Acta Dermato Venereologica”

A patient developed a blister at the injection site after hepatitis C treatment.

research Pinkie, the First Viable Germline Hypomorph Allele of Retinoid X Receptor Alpha, Reveals an Important Role for RXRa in Th2 Development.

2 citations , November 2004 in “Blood”

RXRa is crucial for Th2 immune cell development and may link nutrition to immune health.

research LB793 A phase 1, open-Label, single ascending dose study in healthy subjects of the safety, tolerability and pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha 1 Inhibitor

1 citations , August 2021 in “Journal of Investigative Dermatology”

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

research Ferulic acid promotes hair growth via estrogen receptor alpha activation in cultured human dermal papilla cells

March 2026 in “Scientific Reports”

Ferulic acid may help hair grow by activating certain receptors in cells.

research Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

October 2025 in “Frontiers in Toxicology”

A new method effectively predicts estrogen-related health effects for early screening.

research Finasteride and the 5-Alpha Reductase Inhibitors

October 2025 in “CRC Press eBooks”

research The use of 5 alpha-reductase in the era of minimally invasive surgical therapies (MISTs): Is it still valuable?

September 2024 in “Uro-Technology Journal”

research Identification of Potential Cytochrome p450c 17 Alpha Inhibitors for the Treatment of PCOS via Scaffold Hopping and Fragment-Based De-Novo Drug Design

February 2024

Potential new drugs for treating PCOS were identified.

research Expression and Activity Assay of Human Steroid 5 Alpha-Reductase Type II in CHO Cells

January 2004 in “Pharmaceutical biotechnology”

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

research Structure of human type II 5 alpha-reductase gene

76 citations , September 1992 in “Endocrinology”

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

research Alopecia secondary to anti-tumor necrosis factor-alpha therapy

42 citations , March 2015 in “Anais Brasileiros de Dermatologia”

Anti-TNF therapy can cause hair loss and skin issues.

Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors

research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.

23 citations , January 2001 in “Chemical & Pharmaceutical Bulletin”

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

research Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism

17 citations , October 1994 in “The Journal of Clinical Endocrinology and Metabolism”

research SARS-CoV-2 Infection and Alpha-Synucleinopathies: Potential Links and Underlying Mechanisms

4 citations , November 2024 in “International Journal of Molecular Sciences”

COVID-19 may worsen Parkinson's disease by affecting certain brain proteins.

research A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization

4 citations , November 2022 in “Frontiers in endocrinology”

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond

2 citations , December 2008 in “Journal of Chemical Crystallography”

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

research Increased scalp skin and serum 5 alpha-reductase reduced androgens in a man relevant to the acquired progressive kinky hair disorder and developing androgenetic alopecia

2 citations , September 1997 in “Archives of Dermatology”

research Relative efficacy of minoxidil and 5-alpha-reductase inhibitors in the treatment of male androgenetic alopecia: protocol for a network meta-analysis study

1 citations , May 2021

Expression and Distribution of the Guanine Nucleotide-Binding Protein Subunit Alpha-S in Mice Skin Tissues and Its Association with White and Black Coat Colors

research Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors

1 citations , January 2016 in “Asian-Australasian journal of animal sciences”

The protein GnÎ±s is found more in black mice than white mice and may influence their coat color.

Crystal Structure and Synthesis of 17α-Acetoxy-6,7-Epoxypregn-4-ene-3,20-dione

research Crystal Structure and Synthesis of 17.ALPHA.-Acetoxy-6,7-epoxypregn-4-ene-3,20-dione

1 citations , January 2009 in “X-ray Structure Analysis Online”

A new compound was made that might help treat diseases related to male hormones.

research 0192 Estrogenic effects of 5-alpha-reductase inhibitors in male androgenetic alopecia patients

July 2025 in “Journal of Investigative Dermatology”

research Retinoic-Acid-Related Orphan Receptor Alpha Is Involved in the Regulation of the Cytoskeleton of Hair Follicle Stem Cells

June 2025 in “Biomolecules”

RORA affects hair follicle stem cells' structure and movement, potentially helping treat hair loss.

research The Retinoic-Acid-Related Orphan Receptor Alpha May Be Highly Involved in the Regulation of Seasonal Hair Molting

February 2025 in “International Journal of Molecular Sciences”

RORA plays a key role in controlling seasonal hair molting by affecting hair follicle cell activity.

Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3

research Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3

December 2024 in “Animals”

RORA may help regulate hair growth by affecting hair follicle stem cells.

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