116 citations
,
May 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
114 citations
,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
109 citations
,
January 1980 in “Science of the total environment” Analyzing trace elements in human hair is complex and needs a standardized method.
107 citations
,
May 1999 in “Archives of Dermatological Research” Basal cell carcinoma may start from parts of tiny hair follicles.
105 citations
,
September 1995 in “Journal of The American Academy of Dermatology” Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
101 citations
,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
101 citations
,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
99 citations
,
August 1998 in “Pain” Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
96 citations
,
April 2017 in “Oncotarget” Smaller nanoemulsions can penetrate skin and hair follicles better, which may be useful for delivering drugs and vaccines through the skin.
89 citations
,
January 2001 in “Dermatologic Surgery” Hair loss in women is common, starts in late 20s, and affects 30% of women over 50.
89 citations
,
October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
87 citations
,
March 2017 in “Journal of Clinical Investigation” PSENEN gene mutations can cause both Dowling-Degos disease and acne inversa.
86 citations
,
July 2012 in “British journal of dermatology/British journal of dermatology, Supplement” There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.
85 citations
,
April 2004 in “Thyroid” Thyroid problems can negatively affect women's reproductive health and pregnancy, and can cause symptoms like fatigue and depression, but not all women with these symptoms need treatment.
84 citations
,
November 2003 in “European journal of endocrinology” Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.
83 citations
,
August 2014 in “PLoS ONE” All adults have Demodex mites, which vary by region.
76 citations
,
November 2010 in “Journal of The American Academy of Dermatology” Some African American women's central scalp hair loss is linked to genetics and past fungal scalp infections, with more research needed on other causes.
74 citations
,
January 2013 in “Journal of Investigative Dermatology” Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
72 citations
,
June 2017 in “Zenodo (CERN European Organization for Nuclear Research)” Minoxidil and Propecia are the only FDA-approved hair growth drugs, but concerns about side effects lead people to explore herbal alternatives.
72 citations
,
October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
72 citations
,
January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
68 citations
,
August 2014 in “PeerJ” Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
67 citations
,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
67 citations
,
May 2014 in “International Journal of Molecular Sciences” Using your own skin cells can help repair aging skin and promote hair growth.
66 citations
,
May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
66 citations
,
September 2008 in “Dermatologic therapy” The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
66 citations
,
October 2003 in “Dermatologic clinics” Excision and laser techniques can effectively treat acne keloidalis nuchae.
64 citations
,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
63 citations
,
March 1995 in “International Journal of Dermatology” Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.
63 citations
,
January 1984 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth by increasing cell division and DNA synthesis.