1 citations
,
October 2017 in “Frontiers in Physiology” Hair follicle keratin may have been used in tooth enamel evolution.
The hydrogel helps bone growth and healing in jaw and facial defects.
Thymosin β4 helps with healing, inflammation, and organ protection.
19 citations
,
November 2012 in “Cell Communication and Signaling” FGF-9 speeds up the early development of certain organs, showing potential for organ regeneration.
3 citations
,
December 2020 in “Scientific reports” Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)” Keratin-75 is secreted by ameloblasts in a unique way without a signal peptide.
19 citations
,
December 2015 in “European Journal of Human Genetics” A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.
36 citations
,
November 2005 in “Forensic Science International” BioPlex-11 improves DNA profiling from telogen hair roots in forensic work.
15 citations
,
July 2015 in “Developmental Dynamics” Orai1 protein is crucial for tooth development and affects enamel thickness and mineralization.
28 citations
,
November 2019 in “Gene” The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
210 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
109 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.
February 2026 in “Biomedicine & Pharmacotherapy” MLPH helps hair grow by activating IGF-1 signaling in hair cells.
9 citations
,
August 2013 in “Archives of Dermatological Research” A gene called BMAL1 plays a role in controlling hair growth.
1 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.
5 citations
,
March 2005 in “Journal of The American Academy of Dermatology”
30 citations
,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
December 2017 in “Journal of Cosmetic Dermatology” Researchers found certain genes are overactive and others are underactive in men with early balding, which could help create new treatments.
January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
11 citations
,
November 2023 in “Journal of Advanced Research” Activating ALDH2 can boost hair growth.
16 citations
,
April 1998 in “Journal of Investigative Dermatology” ACTH promotes hair growth in mink, but α-MSH does not.
70 citations
,
December 2004 in “Proceedings of the National Academy of Sciences” BMP signaling affects hair color by interacting with the MC-1R pathway.
October 2025 in “Molecular Genetics and Genomics”
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
13 citations
,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
62 citations
,
December 1966 in “Endocrinology” Injecting α-MSH made mice's hair turn black.
11 citations
,
May 2012 in “Genesis” Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
1 citations
,
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Increased PHGDH expression causes early melanin buildup in hair follicles.
161 citations
,
June 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair stops producing melanin as it transitions from the growth phase to the resting phase.