53 citations
,
January 1993 in “Biochemical Pharmacology” Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.
51 citations
,
June 2021 in “Signal Transduction and Targeted Therapy” The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
38 citations
,
October 2011 in “Analytical biochemistry” Hair proteins have weak spots in their α-helical segments.
26 citations
,
May 2021 in “International Journal of Molecular Sciences” Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
5 citations
,
July 2019 in “Research Square (Research Square)” Yak hair growth is influenced by genes and hormones, helping them adapt to alpine environments.
26 citations
,
December 2021 in “Regenerative Biomaterials” The hydrogel speeds up skin wound healing and helps regenerate tissue.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
4 citations
,
January 2018 in “Elsevier eBooks” Hormones are crucial for regulating body functions and imbalances can lead to health issues.
1341 citations
,
January 2014 in “Cardiology Research and Practice” Managing metabolic syndrome needs both lifestyle changes and medical treatments.
1308 citations
,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
1040 citations
,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
474 citations
,
January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
451 citations
,
March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
441 citations
,
May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
438 citations
,
October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
434 citations
,
October 2003 in “PTR. Phytotherapy research/Phytotherapy research” Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
359 citations
,
September 2017 in “European Journal of Epidemiology” The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
349 citations
,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
336 citations
,
August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
280 citations
,
July 2018 in “Antioxidants” Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
277 citations
,
July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
271 citations
,
March 1999 in “Developmental biology” The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
269 citations
,
May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
266 citations
,
November 2013 in “European Journal of Epidemiology” The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
260 citations
,
July 2010 in “Cell” Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
249 citations
,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
245 citations
,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
233 citations
,
February 2018 in “Polymers” Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.
222 citations
,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.