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Synthetic hormone treatment reduces melanin and hair growth in rats.

Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

Neurosteroids may help treat disorders with too much dopamine activity.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

Short-term diabetes can cause changes in brain steroids, cholesterol balance, and mitochondrial function.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.

Allopregnanolone may enhance alcohol's effects on dopamine neurons, influencing addiction risk.

Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.