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Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.

New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.

Testosterone increases muscle mass regardless of DHT conversion blocking.

OTEC power output is higher in summer due to greater temperature differences.

Scientists made two new chemicals that might help treat diseases caused by male hormones.

New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Researchers made two new compounds that could be used for medicine.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

New genes and pathways are important for testosterone production and male sexual development.

Adrenarche increases adrenal androgens around age 6, affecting hair growth and development.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Men with isolated hypogonadotropic hypogonadism have partial steroid deficiencies, while those with panhypopituitarism have severe deficiencies.

Finasteride was successfully synthesized from Pregnadienolone acetate.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.