116 citations
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September 2001 in “Journal of The American Academy of Dermatology” Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
102 citations
,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
80 citations
,
January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
49 citations
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November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
46 citations
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April 1982 in “Journal of the American Academy of Dermatology” Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.
39 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
30 citations
,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
26 citations
,
May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
23 citations
,
May 2020 in “Cell Death and Disease” Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
17 citations
,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
13 citations
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January 2016 in “Journal of cosmetology & trichology” Alternative treatments show promise for hair growth beyond traditional methods.
11 citations
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August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
10 citations
,
January 2015 in “International Journal of Trichology” Mechanical stress contributes to hair loss in androgenetic alopecia.
9 citations
,
August 2013 in “Archives of Dermatological Research” A gene called BMAL1 plays a role in controlling hair growth.
8 citations
,
February 2010 in “Journal of Dermatology” A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
8 citations
,
October 1988 in “Clinics in Dermatology” Current research explores hair growth drugs, while future research aims for personalized treatments.
7 citations
,
October 2020 in “Journal of Clinical Medicine” Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.
6 citations
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March 2014 in “Herba Polonica” Plant extracts may help treat hormone-related hair loss.
6 citations
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June 2006 in “International Journal of Gynecological Pathology” A postmenopausal woman's hormone imbalance and symptoms improved after removing benign ovarian tumors.
5 citations
,
January 2004 in “Japanese journal of geriatrics” Male hormones can cause hair loss, but treatments like Minoxidil and Finasteride can help, and targeting TGF-B1 could be a future solution.
3 citations
,
November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
2 citations
,
January 2023 in “International Journal of Biological Sciences” A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
2 citations
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May 2018 in “Diagnosis” A 68-year-old woman developed male traits due to a tumor in her ovary, which was removed, returning her hormone levels to normal.
1 citations
,
October 2018 in “InTech eBooks” Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
1 citations
,
March 2018 in “Hair transplant forum international” Using one's own fat may help treat hair loss.
1 citations
,
December 2010 in “Elsevier eBooks” Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
1 citations
,
December 1992 in “International Journal of Dermatology” No significant hormone differences found in postmenopausal women with androgenetic alopecia.
March 2026 in “Frontiers in Pharmacology” New treatments for hair loss show promise but need more testing for effectiveness and safety.
October 2025 in “F1000Research” Postmenopausal women with excess male hormones may have ovarian tumors, and surgery usually cures them.
August 2025 in “Journal of Cosmetic Dermatology” Interest in new and personalized treatments for hair loss is growing.