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Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

5 alpha-reductase inhibitors, like finasteride, are used to treat conditions like prostate issues and skin disorders.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.

Antibody treatments show promise for hair loss but need more research.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

PROTACs show promise for cancer treatment, but designing them effectively is challenging.

Common dermatology drugs were considered but are controversial for COVID-19 treatment.

Exosomes may help stimulate hair growth and improve hair loss conditions like androgenic alopecia.

Both finasteride and drospirenone treatments improved symptoms and increased pregnancy rates in women with polycystic ovary syndrome.

Prenatal and postnatal environments both affect PCOS development and gut microbiota in mice.

Hepatitis B virus alters steroid hormones in male mice, reducing dihydrotestosterone to inhibit viral replication.

CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Targeting ACE2 and TMPRSS2 may help prevent or treat COVID-19 in cancer patients.

Acne is strongly linked to high BMI, hair loss, menstrual issues, family history, and eating too many sweets and fatty foods, but not to excessive hair growth.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

AKR1C3 could be a treatment target for metabolic issues in PCOS.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Apigenin may help promote hair growth and could treat hair loss.