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Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.

Androgen-producing ovarian tumors can cause male-pattern hair loss in women.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.

Androgens can both increase and decrease hair growth in different parts of the body.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

Androgens can both increase body hair and cause scalp hair loss.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Finasteride increases CD8+ T cells in BPH tissues.

Human skin can produce steroids from cholesterol.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Targeting vitamin D and androgen receptors may effectively treat triple-negative breast cancer, especially with chemotherapy.

Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Androgens may block hair growth signals, targeting this could treat hair loss.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Men with testicular cancer were less likely to experience baldness and severe acne.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Minoxidil can reduce functions related to androgen receptors.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Androgen effects on hair follicles vary by skin area.