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Significant progress was made in understanding androgen excess disorders, but much is still unknown.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

PCOS may increase the risk of mental health issues like depression and anxiety.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Androgens affect hair growth and shedding, with genetic and non-genetic factors influencing baldness.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Testosterone treatment may change estrogen receptor methylation in AFAB individuals.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

PCOS involves hormonal imbalance, cysts, and ovulation issues, affecting health and increasing disease risks.

Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.

High AMH levels are linked to PCOS in women and may have a male equivalent with similar traits.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Ultrasound and Doppler analysis are valuable tools for diagnosing and understanding polycystic ovary syndrome.

Plant-based products can improve hair and skin health without harmful side effects.

The link between anabolic agents and colorectal cancer risk is unclear.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

Acne is strongly linked to high BMI, hair loss, menstrual issues, family history, and eating too many sweets and fatty foods, but not to excessive hair growth.

Pu-erh tea reduces hair loss risk in offspring.

Middle-aged women with PCOS often continue to experience symptoms related to high androgen levels, like unwanted hair growth.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Accurate diagnosis and treatment of hyperandrogenism in women require comprehensive evaluation of symptoms and hormone levels.

Targeting the p300/AR axis may help treat polycystic ovary syndrome.

Hair steroid profiling is a feasible, non-invasive alternative to serum analysis for assessing hormone levels and metabolism.

Certain gene changes and hormone levels are linked to female hair loss.