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Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Lowering testosterone speeds up wound healing in male mice.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Testosterone may slow down wound healing and increase inflammation.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Thorough evaluation and surgery are crucial for managing rare ovarian tumors in postmenopausal women with high androgen levels.

AR gene variations don't affect aging markers in men.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Excess androgens may cause PCOS, not just be a symptom.

Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Androgens can both increase and decrease hair growth in different parts of the body.

Sebocytes play a key role in controlling androgen levels in human skin.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.