research Comprehensive clinical management of hirsutism
New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
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research Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome
Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
research Androgenetic alopecia: effects of oral finasteride on hormone profile, reproduction and sexual function
Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
research Comparison of spironolactone and spironolactone plus metformin in the treatment of polycystic ovary syndrome
Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.
research Association of Gly972Arg variant of insulin receptor subtrate-1 and Gly1057Asp variant of insulin receptor subtrate-2 with polycystic ovary syndrome in the Chinese population
The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.
research Controversy: is there a role for adjuvants in the management of male pattern hair loss?
Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.
research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research Adrenal steroid precursors exert potent androgenic action in the hamster sebaceous glands of flank organs and ears.
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research In-vivo uptake and metabolism of testosterone by the skin and other tissues of the rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research Progressive expression of PPARGC1α is associated with hair miniaturization in androgenetic alopecia
Increased PPARGC1α relates to hair thinning in common baldness.
research Endocrinopathies and Other Disorders Inducing a Polycystic Ovary Syndrome Phenotype
Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.
research HSD3B1 gene polymorphism and female pattern hair loss in women with polycystic ovary syndrome
HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.
research Screening of Euphorbiaceae Plant Extracts for Anti-5α-reductase
Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.
research Hirsutism
Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.
research Male Pattern Androgenetic Alopecia
Androgens contribute to common male hair loss; more research needed for hair growth medication.
research The use of testosterone after menopause
Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.
research Testicular Steroidogenesis
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research An update on diagnosis and treatment of female pattern hair loss
Updated treatments for female hair loss include minoxidil, antiandrogens, hair transplants, and light therapy.
research Is TrichoScan a new diagnostic method for diffuse hair loss?
TrichoScan effectively diagnoses different types of hair loss and is linked to low iron stores in patients.
research Gonadal Sex Steroids: Production, Action and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research An overview of female pattern hair loss
Female pattern hair loss involves thinning hair on crown and frontal scalp, diagnosed by hair ratio, and treated with minoxidil, antiandrogens, or hair transplantation.
research Polycystic ovary syndrome: An update on diagnosis and management
PCOS diagnosis and management have improved with new guidelines for personalized care.
research The role of serotonin, ferritin, and hematological profiles in female pattern hair loss
Iron deficiency is linked to female pattern hair loss.
research Menstrual Irregularities in Adolescent Girls and Correlation with the Extent of Exposure to Plastics: A Case-Control Study
Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Serum lipoprotein (a) as an atherosclerosis risk factor in men with androgenic alopecia
Men with male pattern baldness may have a higher risk of heart disease due to increased levels of a specific lipid in their blood.
research ANDROGENETIC ALOPECIA: A REVIEW OF CURRENT THERAPEUTIC OPTIONS
Effective treatments for hair loss include minoxidil, 5α-reductase inhibitors, and personalized combination therapies.
research Effect of Evening Primrose Oil on Hyperandrogenism Markers in Women With Polycystic Ovarian Syndrome
Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.
research Histological and immunohistochemical examination of the effect of the nonsteroidal antiandrogen {flutamide} on some organs of the male reproductive system in albino rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.