May 2015 in “Hair transplant forum international” Androgenetic alopecia causes hair loss by shrinking hair follicles due to androgens, with the connection between the muscle and hair follicle determining if the loss is reversible.
January 2026 in “Journal of Biosciences and Medicines” Androgenetic alopecia treatments focus on reducing hair loss by targeting hormones, with new therapies showing promise but needing more research.
May 2020 in “International journal of molecular biology” Mutations in the AR gene cause hair thinning and loss.
July 2012 in “International Journal of Trichology” Understanding hair health and disorders is important for effective treatment.
Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.
102 citations
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July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
50 citations
,
February 2013 in “Annals of Clinical Biochemistry” Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
45 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Understanding hair follicles through various models can help develop new treatments for hair disorders.
41 citations
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June 2022 in “Biomedicines” PCOS should be reclassified into two types based on hormone levels and symptoms.
26 citations
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December 2020 in “International Journal of Molecular Sciences” Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.
18 citations
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June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
18 citations
,
July 2015 in “Drug Healthcare and Patient Safety” Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.
10 citations
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March 2024 in “Endocrine Reviews” Significant progress was made in understanding androgen excess disorders, but much is still unknown.
10 citations
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January 2015 in “International Journal of Trichology” Mechanical stress contributes to hair loss in androgenetic alopecia.
6 citations
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October 2022 in “International Journal of Molecular Sciences” Male mice with FGF5 mutations grow longer hair than females.
5 citations
,
January 2014 in “Indian Journal of Dermatology” Finasteride is more effective for hair loss in people with body hair.
4 citations
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January 2023 in “Andrology” The testes produce sperm and hormones essential for male development.
3 citations
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May 2018 in “Journal of nutritional health & food science” Nutritional supplements can help manage hair loss and promote hair growth by strengthening hair roots and countering harmful effects of pollution, smoking, and deficiencies in vitamins and minerals.
2 citations
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September 2025 in “Cosmetics” Hormonal therapies can improve skin issues by adjusting hormone levels, with future advancements promising better results.
2 citations
,
July 2022 in “Cell Regeneration” Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
1 citations
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August 2021 in “Arhivʺ vnutrennej mediciny” Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
1 citations
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January 2022 in “European Journal of Pharmacology” Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
August 2025 in “Drug Design Development and Therapy” Current treatments for androgenetic alopecia are complex and promising, but more research is needed.
April 2025 in “Journal of Clinical Medicine” Long-term healthy eating lowers testosterone and improves health in women with suspected PCOS.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
July 2019 in “Journal of Investigative Dermatology” The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
April 2026 in “Inflammation and Regeneration” AKR1C enzymes in scalp glands decrease with age, possibly affecting hair loss.
December 2025 in “Current Issues in Molecular Biology” New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.