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Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Sex hormones do not cause oral lichen planus.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Oral spironolactone's effectiveness for adult female acne is not well-supported by strong evidence.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Certain drugs that block specific enzymes can help treat prostate diseases.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Rats had lasting erectile problems after stopping a certain medication.

Finasteride doesn't affect bone density in male rats.

Early hair loss may indicate prostate issues.

Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.