research Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
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research Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing
A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.
research TGF‐β2 is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Induction of hyperandrogenism and insulin resistance differentially modulates ferroptosis in uterine and placental tissues of pregnant rats
HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
research Female pattern hair loss: beyond an androgenic aetiology? Reply from authors
Hair loss in women may have multiple causes, and eyebrow regrowth possible with specific injections.
research Steroid Hormones of Reproduction and Sexual Development
Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
research Aromatase inhibitors induce ‘male pattern hair loss’ in women?
Aromatase inhibitors cause male pattern hair loss in women.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
research Human scalp hair: Modulation by various factors and hormones do estrogens inhibit or stimulate—A perplexing perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research ST008 Male androgenetic alopecia: A new treatment paradigm
New treatment improves male hair loss.
research Oestrogen functions in skin and skin appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research Gonadal Sex Steroids: Production, Action and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Androgenetic alopecia: An autosomal dominant disorder
Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
research Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research I‐Ascorbic acid 2‐phosphate represses the dihydrotestosterone‐induced dickkopf‐1 expression in human balding dermal papilla cells
Vitamin C derivative reduces hair loss-related protein in cells.
research Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing?
Topical minoxidil improves hair loss in 80% of women with breast cancer undergoing endocrine therapy.
research Skin steroidogenesis in health and disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Sulfatase inhibitors: a patent review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Neuroactive gonadal drugs for neuroprotection in male and female models of Parkinson's disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial
Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
research Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Hirsutism
Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.
research Exploring phytoandrogens: A review of their potential in health and medicine
Phytoandrogens from plants may help treat low testosterone naturally.
research The role of dexamethasone in mediating the contradictory effects of Wnt antagonists SFRP2 and SFRP3 on human hair follicle growth
Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Endocrine Regulation of Hair Growth and Loss: Current Evidence and Clinical Implications
Hormones significantly affect hair growth and loss, requiring personalized treatment.