research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
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research Screening of synthetic and natural product databases: Identification of novel androgens and antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Estrogen and androgen signaling in the pathogenesis of BPH
Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
research Androgens and ovarian function: translation from basic discovery research to clinical impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Basics of androgen synthesis and action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research The Molecular Basis of Androgen Insensitivity
Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
research Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis
Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
research Ovarian sex steroid receptors and sex hormones in androgenized rats
High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research Moxibustion improves ovarian function based on the regulation of the androgen balance
Moxibustion may help improve ovarian function by changing androgen levels.
research Comment on “Androgens and women: COVID‐19 outcomes in women with acne vulgaris, polycystic ovarian syndrome, and hirsutism”
Women with conditions like PCOS may have a higher risk of COVID-19, but treatments like isotretinoin could help those with acne.
research Kelulut Honey Regulates Sex Steroid Receptors in a Polycystic Ovary Syndrome Rat Model
Kelulut Honey can help regulate sex hormone receptors in rats with Polycystic Ovary Syndrome, similar to common medications.
research Effects of vinblastine and its metabolites on nausea and alopecia associated receptors
Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.
research Androgen Signaling in Sertoli Cells
Androgens regulate Sertoli cells and affect fertility through specific receptors and coregulators.
research Modelling androgen synthesis and action during human sexual differentiation
Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
research Discovery of Nonsteroidal Androgens
Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
research Androgen biosynthetic pathways in the human prostate
DHT in the human prostate is produced through multiple pathways, not just from testosterone.
research Androgen sensitivity gateway to COVID ‐19 disease severity
Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
research Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism
Key enzymes control androgen levels, affecting hormone activity and potential treatments.
research Disorders linked to insufficient androgen action in male children
Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
research Androgen‐induced neurite outgrowth is mediated by neuritin in motor neurones
Androgens help motor neurons grow by increasing neuritin.
research Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia
Early onset hair loss linked to genetics and androgen levels.
research THE FIBROBLAST AS A MODEL FOR ANDROGEN RESISTANT STATES
Fibroblasts help understand androgen resistance at the cellular level.
research Anti-Androgen Effects of Extracts and Compounds fromGanoderma lucidum
Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
research Do Anti-androgens Have Potential as Therapeutics for COVID-19?
Anti-androgens might help reduce COVID-19 severity in men.
research Chapter 23. Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research 4 Anti-androgens in gynaecological practice
Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.
research COVID‐19, androgens, and androgenic alopecia
COVID-19 may worsen with androgens; anti-androgen drugs could help.
research A randomized phase II trial on the addition of dutasteride to combined androgen blockade therapy versus combined androgen blockade therapy alone in patients with advanced or metastatic salivary duct carcinoma – the DUCT study protocol
Adding dutasteride to therapy may improve treatment for advanced salivary duct cancer.