research Expanding the Scope of PROTACs: Opportunities and Challenges in Topical Delivery
Topical PROTACs show promise for treating skin conditions but need better stability and delivery methods.
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450-480 / 1000+ resultsresearch Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes
Females have stronger immune responses to COVID-19 than males, leading to better outcomes.
research Reconsidering the Polycystic Ovary Syndrome (PCOS)
PCOS should be reclassified into two types based on hormone levels and symptoms.
research Floral attractants in the black orchid Brasiliorchis schunkeana (Orchidaceae, Maxillariinae): clues for presumed sapromyophily and potential antimicrobial activity
The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.
research Endocrinology
The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
research Pharmacologic interventions in aging hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation
Cathelicidins could treat skin issues but face challenges like safety and resistance.
research Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome
The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
research Hormonal Therapies for Acne: A Comprehensive Update for Dermatologists
Hormonal therapies effectively treat acne and improve quality of life.
research Targeted Self-Assembled anti-NFκB AuNCs-Aptamer Nanoplatform for Precise Theranostics via Tailored Follicle Regeneration
A new treatment using gold nanoclusters can safely reduce unwanted hair growth.
research “MATH+” Multi-Modal Hospital Treatment Protocol for COVID-19 Infection: Clinical and Scientific Rationale
The MATH+ protocol aims to improve COVID-19 outcomes using a combination of specific treatments.
research Human scalp hair: Modulation by various factors and hormones do estrogens inhibit or stimulate—A perplexing perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review
Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
research Linking diet to acne metabolomics, inflammation, and comedogenesis: an update
Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
research Exogenous testosterone, finasteride and castration effects on testosterone, insulin, zinc and chromium in adult male rats.
Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
research Exploring murE protein inhibitors of Tropheryma whipplei through pharmacoinformatic approaches incorporating solubility-enhancing formulation insights
[6]-Gingerdiol 3-monoacetate shows promise for treating T. whipplei infections.
research Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons
Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
research Micronutrients for Hair and Nails
Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
research Clinical review 74: Dermatological manifestations of endocrine disorders.
Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
research Vitamin D, Lipid Metabolism and Prostate Cancer
Vitamin D may help regulate cholesterol and influence prostate cancer development.
research Gender-linked differences in human skin
Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men – short version
Use minoxidil for hair loss treatment; assess results after 6 months.
research A pilot study of ICG laser therapy of acne vulgaris: Photodynamic and photothermolysis treatment
ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
research Revisiting dandruff
Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
research Medicalisation, pharmaceutical promotion and the Internet: a critical multimodal discourse analysis of hair loss websites
Commercial hair loss websites promote Propecia by making men feel insecure about baldness and suggesting it's a medical issue needing treatment.
research ICG laser therapy of acne vulgaris
Near-infrared laser therapy with Indocyanine Green dye improves acne by reducing inflammation without side effects.
research Treatment of acne vulgaris: a literature review / Lečenje običnih akni (acne vulgaris) – pregled literature
The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research The effects of oestrogens on linear bone growth
Oestrogens are key for bone growth during puberty in both boys and girls.