research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
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research Androgen Receptor in Human Health: A Potential Therapeutic Target
The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
research Conventional and novel stem cell based therapies for androgenic alopecia
Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
research Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways
Securinine and ajmaline may effectively treat liver cancer, with securinine being less toxic to normal cells.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research FINASTERIDE INHIBITS 5?-REDUCTASE ACTIVITY IN HUMAN DERMAL FIBROBLASTS: PREDICTION OF ITS THERAPEUTIC APPLICATION IN ANDROGEN-RELATED SKIN DISEASES
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays
The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.
research Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men
A new gene, JMJD1C, may affect testosterone levels in men.
research Exosome-based Therapies for Androgenetic Alopecia: Mechanisms, MicroRNAs, and Clinical Prospects
Exosome therapy could be a promising new way to treat hair loss.
research Alternative treatment of polycystic ovary syndrome: pre-clinical and clinical basis for using plant-based drugs
Plant-based drugs are effective and safe alternatives for managing PCOS symptoms.
research Androgens in women
Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
research The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research New-Generation Therapies for the Treatment of Hair Loss in Men
New treatments for male hair loss show promise but need more research for safety and effectiveness.
research A Study of the androgen receptor gene polymorphism and the level of expression of the androgen receptor in androgenetic alopecia among Egyptians
The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
research Sex differences in COVID-19: the role of androgens in disease severity and progression
Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.
research The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases
Exosomes could revolutionize skin disease treatment and healing.
research Exosomal microRNA-Based therapies for skin diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Revising the role of the androgen receptor in breast cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Multi-therapies in androgenetic alopecia: review and clinical experiences
Multiple treatments work best for hair loss.
research Module-based complexity formation: periodic patterning in feathers and hairs
The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
research Evidence-based approach to cutaneous hyperandrogenism in women
The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research Phytochemicals as emerging therapeutic agents for alopecia treatment
Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails
Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
research Androgenetic Alopecia: An Evidence-Based Treatment Update
Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.
research Androgen insufficiency in women: diagnostic and therapeutic implications
Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
research Cardiovascular risk factors and events in women with androgen excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research Impact of androgen deprivation therapy on mortality of prostate cancer patients with COVID-19: a propensity score-based analysis
Androgen deprivation therapy doesn't lower the risk of death from COVID-19 in prostate cancer patients.