research The Effect of 5 -Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
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research Clinical relevance of testosterone and dihydrotestosterone metabolism in women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone
The normal human prostate does not significantly affect blood DHT levels.
research Clascoterone: First Approval
Clascoterone cream was approved in the USA for treating acne in people aged 12 and older.
research Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals
Estrogen and androgen signals control synaptic changes in rat brains.
research Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes In Vitro
The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
research Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Oral Testosterone in Oil: Pharmacokinetic Effects of 5 Reduction by Finasteride or Dutasteride and Food Intake in Men
Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.
research 5 Dihydrotestosterone metabolism
Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.
research Wanted, dead and alive: Why a multidisciplinary approach is needed to unlock hair treatment potential
Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.
research Steroidogenic enzymes in skin.
Finasteride helps hair growth by reducing DHT levels.
research Management of neonates and children with male pseudohermaphroditism
Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
research 5α-Reductase: History and Clinical Importance
5α-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT levels.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research The endocrinology of baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Skin manifestations associated with COVID-19
COVID-19 can cause various skin issues, like rashes and lesions, which are more common in younger patients and can be linked to more severe complications.
research Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Relations between sex hormone level and characters of hair and skin in healthy young men
Higher androgen levels do not cause baldness in men.
research High circulating oestrone and low testosterone correlate with adverse clinical outcomes in men with advanced liver disease
Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
research Cause of Androgenic Alopecia
Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.
research Male androgenetic alopecia
Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
research Oral Contraceptives as Anti-Androgenic Treatment of Acne
Birth control pills can help reduce mild to moderate acne in women.
research Hirsutism, its pathogenesis
Hirsutism in females is caused by high male hormones or sensitive hair follicles.
research Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research [Hormonal interaction and hair growth].
Hormones, especially DHT, affect hair loss and growth, and targeting specific enzymes may help treat hair loss.
research Finasteride-Induced Gynecomastia in a 62-Year-Old Man
Finasteride caused enlarged breast tissue in a 62-year-old man.
research Effects of Gonadal Steroids on Melanocytes in Developing Hamsters
Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
research Effects of topical application of EGCG on testosterone-induced hair loss in a mouse model
Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.
research Antiandrogen therapy for androgenetic alopecia
Antiandrogen therapy helps treat genetic hair loss.