research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
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research RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.
research Protective effects of melatonin against metabolic and reproductive disturbances in polycystic ovary syndrome in rats
Melatonin may help treat PCOS symptoms in rats.
research INSULIN-LOWERING MEDICATIONS IN POLYCYSTIC OVARY SYNDROME
Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
research The Additive Effects of Minoxidil and Retinol on Human Hair Growth in Vitro
Minoxidil and retinol together help hair grow.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research Selected Abstracts
Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.
research Becker's nevus associated with chromosomal mosaicism and congenital adrenal hyperplasia
High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome
Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes
A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
research Hair Loss in Women
Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.
research Acne-associated syndromes: models for better understanding of acne pathogenesis
The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
research Pharmacology of antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Finasteride for prostatic disease: an updated and comprehensive review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research Update: The Pathogenesis and Treatment of PCOS
New treatments for PCOS focus on managing symptoms and improving fertility.
research TYPICAL MORPHOLOGICAL CHARACTERISTICS OF THE SKIN STRUCTURE OF THE HAIR PART OF THE NORMAL HUMAN HEAD AND WITH HAIR LOSS
Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
research The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research The potential of androgenic alopecia management from plant derivatives
Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
research Polycystic Ovary Syndrome and Its Differential Diagnosis
The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
research Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: What is in common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Transplants from balding and hairy androgenetic alopecia scalp regrow hair comparably well on immunodeficient mice
Hair from balding and non-balding areas regrows similarly on mice.
research Baldness and testicular cancer: the EPSAM case-control study
Bald men may have a lower risk of testicular cancer.
research The evaluation and management of hirsutism*1
Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
research Diagnosis of hyperandrogenism: clinical criteria
The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
research The slick hair coat locus maps to chromosome 20 in Senepol-derived cattle
The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.
research Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb.
Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
research 12 Treatment of hirsutism with 5α-reductase inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research HORMONAL THERAPY IN DERMATOLOGY
Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.
research Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture
Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.