research Anti-androgens for the treatment of hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
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research Female Pattern Hair Loss: a clinical and pathophysiological review
Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
research In vitro hair growth‐promoting effect of Lgr5‐binding octapeptide in human primary hair cells
A synthetic octapeptide may help promote hair growth and counteract hair loss.
research Antiandrogens and Androgen Inhibitors
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
research Nonscarring hair loss disorders
Most types of hair loss can regrow naturally, but there are no effective cures for male pattern or age-related hair loss, and only limited options for females.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research HAIR AND SYSTEMATIC DISEASE
Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
research PHARMACOLOGICAL BASIS FOR CLINICAL USE OF ANTIANDROGENS
Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.
research Germination Enhances Phytochemical Profiles of Perilla Seeds and Promotes Hair Growth via 5α-Reductase Inhibition and Growth Factor Pathways
Germinated perilla seeds can naturally promote hair growth and prevent hair loss.
research LncRNA-000133 from secondary hair follicle of Cashmere goat: identification, regulatory network and its effects on inductive property of dermal papilla cells
A newly found RNA in Cashmere goats may play a role in hair growth and development.
research An Exploratory In Vivo Study on the Effect of Annurca Apple Extract on Hair Growth in Mice
Annurca apple extract improved hair growth in mice and could potentially prevent hair loss.
research (7E)-7,8-Dehydroheliobuphthalmin from Platycladus orientalis L.: Isolation, Characterization, and Hair Growth Promotion
DHHB from Platycladus orientalis L. promotes hair growth and could be a natural alternative to current treatments.
research Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup
Targeting CXCL12 may help treat hair loss caused by androgens.
research β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress
NMN could potentially treat hair loss by reducing oxidative stress and improving cell health.
research Androgen effects on the skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research The physiological and pharmacological roles of prostaglandins in hair growth
Targeting the PGD2-DP2 pathway may help treat hair loss.
research Comparison of In Vitro Hair Growth Promotion and Anti-Hair Loss Potential of Thai Rice By-Product from Oryza sativa L. cv. Buebang 3 CMU and Sanpatong
Et-BB3-CMU rice bran extract may be a promising natural option for promoting hair growth and preventing hair loss.
research Expression and functional relevance of melatonin receptors in hair follicle biology
Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
research Hair growth-promotion effects at the cellular level and antioxidant activity of the plant-based extract Phyllotex™
Phyllotex™ extract was found to significantly promote hair growth and protect against hair loss.
research Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche
Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
research Pilose antler extract promotes hair growth in androgenic alopecia mice by promoting the initial anagen phase
Pilose antler extract helps hair grow in mice with a type of hair loss by speeding up the growth phase.
research Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
research Lack of a gonadal or adrenal androgenic mechanism for the hypertrichosis produced by diazoxide, phenytoin and minoxidil
These drugs cause hair growth without affecting testosterone or adrenal hormones.
research Menopause and hair loss in women: Exploring the hormonal transition
Menopause can cause hair loss in women due to hormonal changes, affecting their well-being and quality of life.
research Hirsutism
Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
research Diagnosis and treatments of hirsutism: where are we?
Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.
research Alopecia: managing the basics
The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.
research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
Hormones and genes affect hair growth and male baldness.
research Subcutaneous injection of genetically engineered exosomes for androgenic alopecia treatment
EX104 shows promise in treating hair loss by promoting hair growth and improving scalp health.