research Causal effects of omega‐6 and LDL‐C on androgenetic alopecia: A Mendelian randomization study
Omega-6 and LDL cholesterol increase the risk of hair loss.
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research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Metabolite identification by mass spectrometry of the 5α-reductase inhibitor finasteride in vitro and in vivo
Finasteride's metabolites were identified, helping understand how the drug is processed in the body.
research The effect of St John’s Wort treatment on finasteride metabolism and identification of new finasteride metabolites in humans
St John’s Wort can change how finasteride works in the body.
research Determination of finasteride and its metabolite in urine by dispersive liquid–liquid microextraction combined with field-enhanced sample stacking and sweeping
New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
research Preparation of3H-labelled testosterone metabolites
The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
research Lactiplantibacillus plantarum ZJUIDS51 improves androgenic alopecia via gut-skin axis
Lactiplantibacillus plantarum ZJUIDS51 can help regrow hair and improve scalp health in androgenic alopecia.
research Anti-Androgenicity of Flutamide and its Metabolite Sch 16423
Flutamide and its metabolite can effectively reduce androgen effects.
research 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism.
High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Effects of vinblastine and its metabolites on nausea and alopecia associated receptors
Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.
research Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms
Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways
Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
research Antiaging effects of equol: A unique antiandrogenic isoflavone metabolite and its influence in stimulating collagen deposition in human dermal monolayer fibroblasts
Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.
research Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of the Literature
A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.
research Rare and common genetic determinants of metabolic individuality and their effects on human health
Genetic variations greatly affect individual metabolism and can impact health and disease risk.
research Urinary steroids in men with male-pattern alopecia
Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
research Efektifitas Panax Ginseng terhadap Alopecia
Panax Ginseng may help prevent hair loss.
research Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method
Prepubertal girls have higher sex steroid levels than boys, possibly leading to earlier puberty.
research Verstärkter Haarwuchs unter Langzeittokolyse mit Fenoterol** unter Berücksichtigung von Testosteron, Androstandiol, Cortisol und ACTH*
Fenoterol treatment causes increased hair growth due to higher metabolism in hair follicles, not hormones.
research Alopecia and the Microbiome: A Future Therapeutic Target?
The microbiome may be linked to hair loss and could be a target for new treatments.
research Nonscarring alopecias
Male pattern hair loss affects up to 80% of men due to genetics and hormone sensitivity.
research Urinary 5-ene-steroid excretion in non-classical congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency (NC-3BHSD)
Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.
research Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride
Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
research A Teenage Girl with Unexpected Pubertal Changes
The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
research Long-term detection of methyltestosterone (ab-) use by a yeast transactivation system
A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.
research Interaction of spironolactone with rat skin androgen receptor
Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
research More about X‐linked testicular feminization of the mouse as a noninducible (is) mutation of a regulatory locus: 5α‐androstan‐3α‐17ß‐diol as the true inducer of kidney alcohol dehydrogenase and ß‐glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
research Untargeted metabolomics and steroid signatures in urine of male pattern baldness patients after finasteride treatment for a year
Finasteride treatment changes certain urine metabolites in male pattern baldness patients.