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DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

Estrogen and androgen signals control synaptic changes in rat brains.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Finasteride and dutasteride may cause depression and anxiety, especially in younger men.

Neurosteroids help control dopamine responses in the brain.

Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Gene expression differences in PFS patients suggest a potential organic cause for symptoms.

Finasteride can cause serious mental health issues, so it's advised to avoid it for hair loss.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride use doesn't cause sexual dysfunction in men with hair loss.

Glioblastoma cells can make androgens, which might help the tumor grow.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Neurosteroids show promise for treating epilepsy and more research is needed.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.