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research C19and C215β/5αMetabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency*
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research Theoretical evaluation of interaction of some dibenzo derivatives on both androgen receptor and 5α-reductase enzyme
Certain Dibenzo derivatives may help treat prostate cancer.
research Androgenetic Alopecia
research The Effects of Transdermal Dihydrotestosterone in the Aging Male: A Prospective, Randomized, Double Blind Study
Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
research In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5α-reductase inhibitors
The new compounds may be more effective and cheaper than current treatments for conditions like baldness.
research Intracrine androgen biosynthesis, metabolism and action revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Effects of 5-alpha reductase inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
research Impact of estrogens in males and androgens in females
Both estrogens and androgens are important for health in both males and females.
research Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
research 319 Acne, androgenetic alopecia, and atopic dermatitis in transgender patients on hormone therapy: A retrospective comparative cohort study
Transgender patients on hormone therapy experience more acne and hair loss, but less skin inflammation.
research Clinical and epidemiological characteristics and condition of the hormonal status in women with androgenetic alopecia (1139.3)
Women with androgenetic alopecia often have other symptoms of high androgen levels, requiring further hormone testing.
research Transmasculine Hormone Therapy
Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.
research In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands
Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
research Cellular actions of testosterone in vascular cells: Mechanism independent of aromatization to estradiol
Testosterone affects vascular cells directly without converting to estradiol.
research In vitro bioassays for androgens and their diagnostic applications
In vitro bioassays are better than traditional methods for measuring androgen activity but aren't ready for routine use yet.
research Skin manifestations of hyperandrogenism: an update
Targeting androgen receptors in the skin is the most effective treatment for hyperandrogenism-related skin issues.
research An unusual circulating steroid profile in a virilized postmenopausal woman
A 68-year-old woman developed male traits due to a tumor in her ovary, which was removed, returning her hormone levels to normal.
research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone
The normal human prostate does not significantly affect blood DHT levels.
research Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5α-reductase inhibitor
Combining 5α-reductase and aromatase inhibitors may better reduce estrogen levels.
research Features of steroidogenesis and arterial hypertension in men in different types of "physiological" male hyperandrogenism
Men with high testosterone may have higher morning blood pressure, unlike those with high DHT.
research Testosterone enantate
A man developed hair loss from testosterone treatment but improved with additional medication.
research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping
PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
research Urinary Androgens Provide Additional Evidence Related to Metabolism and Are Correlated With Serum Androgens in Girls
The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.
research Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia
DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
research Androgenetic Alopecia
research Androgens and erythropoiesis. Induction of erythropoietin-hypersecretory state and effect of finasteride on erythropoietin secretion
Androgens increase EPO production, finasteride doesn't significantly impact it.
research ROLE OF PLATELET-RICH PLASMA IN ANDROGENETIC ALOPECIA: A PROSPECTIVE STUDY
research Evaluating 5 alpha reductase inhibitors for the treatment of male androgenic alopecia
Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.
research Östrogen-induzierte Gynäkomastie nach Anwendung östrogenhaltiger Lokaltherapeutika
Estrogen treatments can cause unwanted effects in men and should be used cautiously.