research Clinical and dermoscopic patterns of childhood alopecia areata in a tertiary care centre in North India
No link between scalp patterns and alopecia severity in children, but more severe cases often had nail abnormalities.
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960-990 / 1000+ results research Sexual adverse events-related to dutasteride e finasteride: analysis of real-life data from Eudra-Vigilance database
research Ritlecitinib for the Management of Alopecia Areata: A Narrative Review of Real-World Evidence and Selected Post Hoc Analyses
Ritlecitinib, a selective JAK3 and TEC family kinase inhibitor, has shown promise as a targeted systemic therapy for moderate-to-severe alopecia areata (AA). This narrative review analyzed 14 studies, including real-world observational studies and post hoc analyses, to assess its effectiveness and safety. Results indicate sustained efficacy with progressive improvement in SALT scores over 24 months and meaningful hair regrowth in diverse populations, including severe and pediatric cases. Factors such as lower baseline severity and shorter disease duration were linked to better responses. The safety profile was favorable, with mostly mild adverse events. The findings highlight the importance of early intervention and adequate treatment duration, though further large-scale studies are needed to refine patient selection and response predictors.
research Health hazard evaluation report: HETA-2000-0385-2813, Equifax Payment Services, St. Petersburg, Florida.
The investigation found no work-related causes for employee hair loss at Equifax Payment Services, and the environment was not hazardous.
research Episodic Bilateral Corneal Edema Caused by Hair Groom Gel
research Pediatric Inpatients Requesting Dermatology Consultation in a Tertiary Care Hospital: Retrospective Analysis of 614 Patients
Most pediatric inpatients needed dermatology consultations for unspecified rashes and drug reactions, with varied treatments.
research Dermatological history and examination
A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.
research Disconnect Between Patient and Dermatologist Perceptions in Androgenetic Alopecia Therapy: Social Analysis Across More Than 100,000 Digital Conversations
People prefer over-the-counter hair loss treatments despite better evidence for prescriptions, leading to delayed care.
research Focal Asymptomatic Hair Loss in an Adolescent: A Case Report
A 13-year-old boy had a rare, stable type of hair loss with little chance of regrowth, but treatment is available for looks.
research The effects of autologus platelet rich plasma and various growth factors on non-transplanted miniaturized hair
PRP treatment helped reverse hair thinning and promoted new hair growth.
research Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice
TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.
research Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice
TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.
research Renbök phenomenon in a child: A new case and review of paediatric cases
research Patient-reported Outcomes of Adverse Events After Perioperative Chemotherapy for Breast Cancer: A Prospective Observational Study
Some side effects of breast cancer chemotherapy, like neuropathy and nail loss, can last long after treatment.
research Integrated safety analysis of baricitinib in adults with severe alopecia areata from two randomized clinical trials
Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
research FOCAL HYPERTRICHOSIS DURING TOPICAL TACROLIMUS THERAPY FOR CHILDHOOD VITILIGO
An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
research Health hazard evaluation report: HETA-2000-0176-2829, The Centre for Well-Being at The Phoenician Resort, Scottsdale, Arizona.
Improve ventilation and address environmental issues to reduce health complaints.
research Oral finasteride use and sexual adverse events: signal detection from disproportionality analyses of data from the United States Food and Drug Administration Adverse Event Reporting System
Oral finasteride may cause more sexual side effects than expected, possibly due to negative publicity and reporting bias.
research Evaluation of dermatologic adverse events associated with aromatase inhibitors: insights from the FAERS database
Aromatase inhibitors can cause skin issues, especially with anastrozole and exemestane, so monitoring is important.
research A case report and literature review of delayed telogen effluvium after topical imiquimod use in treating a cervical high-grade squamous intraepithelial lesion
Topical imiquimod use for treating a cervical lesion might cause delayed hair loss.
research Clinical and demographic factors associated with nail involvement in adult alopecia areata patients at Al-Kadhmia teaching hospital, Baghdad, 2023
Nail changes in alopecia areata are common and may indicate severity and genetic risk.
research BH29 Psychological distress in alopecia areata: are we doing enough?
A retrospective audit of 25 patients with alopecia areata (AA) at a secondary care dermatology clinic revealed significant psychological distress and impaired quality of life, with 66% experiencing severe disease and 76% having comorbidities. Despite BAD guidelines recommending routine psychological assessment and support, only 16% underwent formal mental health screening, and referrals to psychological services were rare. The study highlights a gap between guidelines and practice, suggesting that the true psychological burden is underestimated due to time and structural constraints in NHS clinics. The authors propose an integrated care model with routine psychological screening, dedicated nursing support, and tailored resources to improve care for AA patients.
research Aseptic and Alopecic Nodule of the Scalp in a Young Female With Alopecia Areata
Intralesional steroids effectively treated a young female's scalp nodules without recurrence.
research Patient‐reported outcomes of topical finasteride/minoxidil treatment for male androgenetic alopecia: A retrospective study using telemedical data
Topical finasteride/minoxidil is effective but not better than oral finasteride for hair loss.
research SUMMARIES OF PAPERS
The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.
research 20th Annual Symposium of the British Society of Paediatric Dermatology, 11-12 November 2005, Newcastle upon Tyne, U.K.
The document reports unique growth lines in a child after Stevens-Johnson syndrome, skin reaction from parsnips and sun in a girl, and itchy skin with xanthomas in a boy with Alagille syndrome.
research Trichotillomania Mimicking Alopecia Areata in an Adolescent Girl: A Clinicopathologic Case Report
This case report discusses a 16-year-old girl with trichotillomania, a condition characterized by compulsive hair pulling, which can mimic alopecia areata. The patient presented with frontal scalp alopecia and thinning of eyebrows and eyelashes. Dermoscopic and histopathologic examinations confirmed trichotillomania by revealing specific hair and follicle characteristics. Despite a psychiatric referral, the family declined structured psychiatric management due to sociocultural barriers. The report emphasizes the need for clinicopathologic correlation to differentiate trichotillomania from alopecia areata and highlights the psychosocial challenges in managing adolescent patients with this condition.
research Alopecia Areata in Skin of Color: Trichoscopic Analysis in Black/African American Patients
Better documentation of alopecia areata in Black individuals is needed to improve diagnosis.
research Peer Review Report For: Pattern changes of cutaneous dermatoses among Iraqi women preceding and during the COVID-19 pandemic [version 3; peer review: 2 approved]
During COVID-19, Iraqi women saw more hair loss and skin issues like acne due to stress, masks, and hygiene habits.
research Angiokeratomas Scroti Associated with Angiokeratomas of the Eyelids: Coincidence or One Entity? A Case Report and Review of the Literature
The report suggests that the same underlying issue in blood vessel support may cause angiokeratomas on both the scrotum and eyelids.