research Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea regia Fruits, in the Male Rat: A Comparison with Finasteride
D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
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research Finasteride as a positive control on reproduction studies
Finasteride causes reproductive malformations in male rats.
research Comments on “Maternal–fetal safety evaluation of an aqueous extract of Casearia sylvestris [AECS ] leaves in rats” (Nagaoka et al., 2023 [DOI : 10.1002/bdr2.2257])
The commentary stresses the importance of using historical control data and proper interpretation in evaluating developmental toxicity.
research El finasteride como control positivo en estudios de reproducción
Finasteride causes reproductive changes in male rats.
research Finasteride use during pregnancy and early neonatal outcome: a case report
Baby born healthy despite mom taking finasteride, but more research needed.
research Follicular Neutrophilic Inflammation (Hidradenitis Suppurativa)
Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.
research 3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa
Scientists created a 3D skin model to study a chronic skin disease and test treatments.
research Environmental Factors and Puberty Timing: Expert Panel Research Needs
Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
research Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors
Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
research Mixed “Antiandrogenic” Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat
Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
research Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research Testosterone therapy in women: Myths and misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Health-related quality of life in women with polycystic ovary syndrome attending to a tertiary hospital in Southeastern Spain: a case-control study
Women with Polycystic Ovary Syndrome (PCOS) have a lower health-related quality of life, especially those with an anovulatory phenotype, and may need specific interventions to improve it.
research Rodent models in placental research. Implications for fetal origins of adult disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Prenatal Androgenization of Ewes as a Model of Hirsutism in Polycystic Ovary Syndrome
Prenatally androgenized ewes can model increased hair diameter in women with PCOS.
research Assessment of Optimism in Women with Polycystic Ovary Syndrome: A Case Control-Study
Women with PCOS tend to be less optimistic than those without it.
research Retardation of Preputial Wound Healing in Rats with Hypospadias Induced by Flutamide
Flutamide-induced hypospadias in rats slows down early wound healing.
research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
research Female Antiandrogens
Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
research Evaluation of Some Hormones Total Antioxidant Capacity and Malondialdehyde Levels in Polycystic Ovarian Syndrome Women attending the gynecology Clinic at Nnewi
Women with PCOS have higher oxidative stress and hormone imbalances, suggesting managing oxidative stress could help.
research Health-related quality of life in adult Mediterranean women with polycystic ovary syndrome attending to a tertiary hospital: a case-control study.
Women with PCOS have worse physical health but similar mental health compared to those without PCOS.
research Efectos de la alteración de los niveles de allopregnanolona durante periodos críticos del neurodesarrollo en la vulnerabilidad al consumo de alcohol
Early NAS level changes affect alcohol consumption vulnerability.
research Histological and immunohistochemical examination of the effect of the nonsteroidal antiandrogen {flutamide} on some organs of the male reproductive system in albino rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research The Use of Finasteride in Treating Androgenetic Alopecia in Adult Men
Finasteride effectively treats mild to moderate hair loss in men aged 18-41, with some side effects.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Change of the diagnostic distribution in applicants to dermatology after COVID ‐19 pandemic: What it whispers to us?
The COVID-19 pandemic led to fewer dermatology visits and changed the types of skin conditions patients experienced.
research Characterization of Novel Cutaneous Human Papillomavirus Genotypes HPV-150 and HPV-151
HPV-150 and HPV-151 are rare skin viruses linked to warts and some skin cancers.
research The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia
Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.