research Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse
Scube3 gene affects mouse embryo growth in multiple areas, but needs more research.
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960-990 / 1000+ results research Three-dimensional analyses of touch domes in the hairy skin of the cat paw reveal morphological substrates for complex sensory processing
Cat paws have complex touch sensors for detailed sensory processing.
research FINASTERIDE AND PSA
research 876 Imaging nanoscale changes in desmosome protein organization
Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.
research Overview of the Role of 308 Monochromatic Excimer Phototherapy for the Treatment of Alopecia Areata
308 excimer phototherapy is a safe and effective way to treat hair loss from Alopecia Areata.
research Generation of functionally active resident macrophages from adipose tissue by 3D cultures
3D cultures can create active macrophages from fat tissue.
research Mapping the hair density, thickness, and volume in normal and androgenetic alopecia subjects with the digital microscope
Hair density and thickness decrease in specific scalp areas in people with androgenetic alopecia.
research 555 Dermal single-cell atlas: a novel tool to explore fibroblast heterogeneity
A new tool helps study hair follicle cells to develop better treatments for hair disorders.
research New approach to 3-oxo-4-aza-5α-androst-1-ene-17β-(--butylcarboxamide)
A new method was developed to make finasteride for treating hair loss.
research The 3D Bioprinted Scaffolds for Wound Healing
3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
research The efficacy of a photolyase-based device on the cancerization field: a clinical and thermographic study
The photolyase-based device significantly changed the size and heat of potential skin cancer areas in patients.
research Chaotrope-Guided Protein Microneedles with High Drug-Loading Capacity, Ultrafast Dissolution, and High Mechanical Strength
research BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens
BroadAMP-GPT is an innovative AI-driven platform designed to efficiently generate and validate antimicrobial peptides (AMPs) to combat multidrug-resistant ESKAPE pathogens. The study found that 57% of AI-generated AMPs were effective against these pathogens. A standout candidate, AMP_S13, exhibited remarkable stability across various physiological conditions and demonstrated low toxicity. It also proved effective in vivo, reducing mortality in an infection model and promoting wound healing in a skin infection model. This platform represents a significant advancement in the rapid discovery of stable, broad-spectrum AMPs with low toxicity, addressing the critical issue of antimicrobial resistance.
research A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing
The DiLiCre mouse model is an effective tool for precise genome editing using light.
research Multiple Retinal Emboli and Medial Canthal Swelling Following Injection of Acellular Porcine Urinary Bladder Matrix for Hair Restoration
A woman had eye pain and vision loss after a hair growth treatment, but her symptoms improved after a month.
research Effectiveness of 308-nm Excimer Laser Therapy in Treating Alopecia Areata, Determined by Examining the Treated Sides of Selected Alopecic Patches
308-nm excimer laser therapy helps regrow hair in alopecia areata.
research Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells
Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.
research Poster abstract: Novel dissolving microarray patches for intradermal delivery of finasteride
Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.
research Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research Retinoic Acid and Mouse Skin Morphogenesis. I. Expression Pattern of Retinoic Acid Receptor Genes During Hair Vibrissa Follicle, Plantar, and Nasal Gland Development
research Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
A new method allows detailed tracking of cell regeneration in crustacean legs.
research Bioprinted Recombinant Human-Collagen-Based In Vitro Skin Models for Assessing Effects of Nano-ZnO on Dermis
In this study, researchers developed a biomimetic 3D skin model using methacrylated recombinant human collagen bioinks to assess the effects of nano-zinc oxide (nano-ZnO) on skin. The model, which mimics the skin of children and adults, includes dermal layers with human skin fibroblasts and human umbilical vein endothelial cells, as well as epidermal layers with keratinocytes. It successfully replicates native skin architecture and allows for the evaluation of key markers. The study found that nano-ZnO significantly affects genes related to apoptosis, inflammation, and oxidative stress in skin cells, highlighting its potential impact on skin health.
research Application of multiphoton microscopy in dermatological studies: A mini-review
Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
research Hair Growth-Promoting Effects of a Multi-Targeted Cosmetic Formulation Containing PYGL, DP2, and 15-PGDH Inhibitors Developed Using AI-Based DeepZema® in Androgenetic Alopecia: A 24-Week Randomized Controlled Trial
The formulation significantly increased hair density and thickness safely in people with androgenetic alopecia.
research 1310 Anti-aging effects of retinoid hydroxypinacolone retinoate on skin models
Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.
research Intestinal Stem Cell Imaging in Colorectal Cancer Screening
Imaging intestinal stem cells might help detect early signs of colorectal cancer.
research Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
The study introduced a technique called two-photon chemical apoptotic targeted ablation (2Phatal), which allowed for precise induction and visualization of apoptosis in living animals using a femtosecond-pulsed laser. This method enabled targeted ablation of specific cell types, such as neurons, glia, and pericytes, in the mouse brain and zebrafish without causing collateral damage. By combining 2Phatal with organelle-targeted fluorescent proteins and biosensors, researchers discovered previously unknown differences in apoptosis patterns and dynamics among cell types, including ribosomal disassembly, calcium overload, and mitochondrial fission. The technique offered a powerful tool for studying the functional consequences of cell death, neural plasticity, and tissue remodeling across various organs and species.
research Synergistic effect of carbodiimide and dehydrothermal crosslinking on acellular dermal matrix
Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.
research Autologous Micrograft Technology (AMT) and Finasteride for the Management of Androgenic Alopecia – A Systematic Review and Meta-analysis of the Efficacy and Safety
AMT may be more effective than finasteride for hair growth in androgenetic alopecia.