38 citations
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January 2002 in “Biological & Pharmaceutical Bulletin” Lygodii Spora extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.
11 citations
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January 1985 in “Archives of Dermatology” Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.
9 citations
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June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
7 citations
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July 2019 in “Scientific Reports” Finasteride helps reduce heart enlargement in heart failure patients.
5 citations
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October 2010 in “General and Comparative Endocrinology” Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
4 citations
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November 1996 in “European journal of endocrinology” Spironolactone may help treat excessive hair growth in girls, but more research is needed.
1 citations
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July 2024 in “Frontiers in Pharmacology” The woman delivered a healthy baby boy despite taking spironolactone during pregnancy.
41 citations
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March 2007 in “Steroids” New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
3 citations
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January 2018 in “Reproduction, Fertility and Development” Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
1 citations
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November 2024 in “Life” Desmodesmus pannonicus water extract may help reduce skin pigmentation, heal wounds, and promote hair growth.
January 2024 in “Pediatric Dermatology” Minoxidil improved hair growth in a child with a rare genetic disorder.
18 citations
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January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
39 citations
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November 1978 in “Annals of internal medicine” Spironolactone may help reduce excessive hair growth in women with high male hormone levels.
23 citations
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July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
9 citations
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April 2011 in “PubMed” Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.
1 citations
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January 2015 in “Elsevier eBooks” Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
May 2026 in “Quality in Sport” Berberine may help improve insulin sensitivity, hormone balance, and reproductive function in women with PCOS.
August 2025 in “JAAD International” Bicalutamide may take longer to work for female hair loss, and higher doses might be needed.
November 2011 in “DOAJ (DOAJ: Directory of Open Access Journals)” Oral contraceptives can help manage acne by reducing androgen levels.
64 citations
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March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
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January 2004 in “Drugs” Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.
11 citations
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January 1985 in “British Journal of Dermatology” The document concludes that an inherited nail condition often improves on its own, and spironolactone effectively treats acne in women.
6 citations
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January 2017 in “Dermato-endocrinology” ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.
3 citations
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September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
72 citations
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June 1979 in “Biochemical Society Transactions” Flutamide and its metabolite can effectively reduce androgen effects.
45 citations
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August 2005 in “Bioorganic & medicinal chemistry” New compounds with carborane showed anti-androgen effects similar to flutamide.
1 citations
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January 2022 in “European Journal of Pharmacology” Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
December 2025 in “The International Journal of Medical Science and Health Research” Rosemary may effectively treat hair loss with fewer side effects than conventional treatments.
1 citations
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January 1989 in “Handbook of experimental pharmacology” Anti-androgens can help reduce the effects of male hormones on the skin.
September 2025 in “Dermatology and Therapy” The treatment improved hair growth and was well-received without side effects.