research DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho−/− mice
Linagliptin slows down premature aging in certain mice.
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960-990 / 1000+ resultsresearch Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging
Hair follicle stem cells change states with age, affecting hair growth and aging.
research STEROID HORMONES IN GERIATRICS
Steroid hormones can help treat aging issues and improve health in elderly people.
research Shen-Ying-Yang-Zhen formula promotes angiogenesis around hair follicles, alleviates oxidative stress, and inhibits hair follicle apoptosis through the VEGF/Akt/Caspase-9 signaling axis
The formula may improve hair growth and health by boosting blood flow and reducing cell stress.
research Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform
CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.
research Geriatric dermatology, changes related to aging
Skin changes naturally as we get older.
research P02 Accelerated ageing of hair follicles in androgenetic alopecia
Hair follicles in androgenetic alopecia age faster, especially in the front.
research Effects of olive leaf extract supplementation on systemic markers of tissue aging and remodeling in postmenopausal women: a randomized controlled trial with exploratory skin outcomes
Olive leaf extract may help reduce aging signs in postmenopausal women.
research Clinical spectrum of ageing versus non-ageing geriatric dermatoses -A case-controlled study in tertiary care centre, Tamil Nadu, South India
Older people more commonly have skin conditions related to aging, and early treatment can improve their quality of life.
research 1396 Interferon-24 regulates the expression of MMP1 and dermal collagen of the skin
IL-24 contributes to skin aging by increasing collagen-degrading enzymes and decreasing collagen production when exposed to air pollution.
research Age-induced hair greying - the multiple effects of oxidative stress
Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
research Aging in the Male Face: Intrinsic and Extrinsic Factors
Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.
research 516 Intrinsic factors regulating hair growth: insights into growth factors, cytokines, chemokines, and interferons
Red ginseng components help prevent skin aging by reducing inflammation and improving cell function.
research Ageing and colony-forming efficiency of human hair follicle keratinocytes
Aging reduces the ability of human hair follicle cells to form new cell colonies.
research Effects of Glucagon-like Peptide-1 Receptor Agonists on Skin Homeostasis and Skin Aging Processes
GLP-1 RAs may help wound healing but can also cause faster facial aging and skin issues.
research Effect of estrogens on skin aging and the potential role of SERMs
Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Tideglusib promotes wound healing in aged skin by activating PI3K/Akt pathway
Tideglusib helps heal wounds in older skin.
research O21 Single-cell RNA sequencing and proteomic analysis of dermal fibroblasts cultured from female scalp identifies significant alterations in cell populations with age
Aging changes scalp cells, possibly affecting hair health in older women.
research A Multifaceted View on Ageing of the Hair and Scalp
Proper scalp care can improve hair health and delay ageing signs.
research PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair
PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Autophagy helps delay aging in mouse glands, maintains fat balance, and controls scent production.
research Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging
As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
research An overview about Therapeutic uses, clinical efficacy, safety and classes of Retinoids and its efficacy for Treatment of skin aging
Retinoids effectively treat skin aging but have safety and stability issues.
research Fibroblast‐derived growth factors and exosomes as cosmeceuticals
Fibroblast-derived growth factors and exosomes can significantly improve skin aging.
research Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts
Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
research Mucosal TLR5 activation controls healthspan and longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Investigation of the crosstalk between proteasome function and nucleotide excision repair mechanism during ageing
The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.
research Clinical Snippets
Melanoma risk tools need improvement, a gene mutation causes a hair disorder that might be treated by managing cell stress, a potential therapy for a skin-ear disorder involves blocking cell channels, skin wrinkling may indicate lung aging regardless of smoking, and oxidative stress might contribute to common baldness.
research Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation
Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.