September 2022 in “Frontiers in Immunology” Anti-androgen therapy may boost immunity but increases injection site pain in vaccinated patients.
December 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Flutamide, an oral anti-androgen therapy, is effective in treating female pattern hair loss, even without systemic androgen excess.
9 citations
,
October 2018 in “Medical Science Monitor” Lowering certain hormone levels improves treatment for hair loss in young men.
40 citations
,
January 1994 in “Skin Pharmacology and Physiology” Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
190 citations
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October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
7 citations
,
August 2010 in “Medicinal Chemistry Research” Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
21 citations
,
June 2010 in “Anais Brasileiros De Dermatologia” The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.
1 citations
,
July 2024 in “Frontiers in Pharmacology” The woman delivered a healthy baby boy despite taking spironolactone during pregnancy.
41 citations
,
March 2007 in “Steroids” New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
9 citations
,
June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
9 citations
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April 2011 in “PubMed” Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.
5 citations
,
May 1994 in “Facial plastic surgery clinics of North America” Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.
4 citations
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November 1996 in “European journal of endocrinology” Spironolactone may help treat excessive hair growth in girls, but more research is needed.
3 citations
,
January 2018 in “Reproduction, Fertility and Development” Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
August 2025 in “JAAD International” Bicalutamide may take longer to work for female hair loss, and higher doses might be needed.
November 2011 in “DOAJ (DOAJ: Directory of Open Access Journals)” Oral contraceptives can help manage acne by reducing androgen levels.
February 1976 in “PubMed” Sex hormone therapy is effective for certain skin conditions like acne and seborrhea, but less so for female hair loss and excessive hair growth.
88 citations
,
June 2016 in “Human Reproduction Update” New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
1 citations
,
January 2015 in “Elsevier eBooks” Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
124 citations
,
September 1980 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Spironolactone is effective in treating excessive hair growth in women.
39 citations
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November 1978 in “Annals of internal medicine” Spironolactone may help reduce excessive hair growth in women with high male hormone levels.
23 citations
,
July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
1 citations
,
November 2024 in “Life” Desmodesmus pannonicus water extract may help reduce skin pigmentation, heal wounds, and promote hair growth.
May 2026 in “Quality in Sport” Berberine may help improve insulin sensitivity, hormone balance, and reproductive function in women with PCOS.
64 citations
,
March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
18 citations
,
January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
1 citations
,
January 2004 in “Drugs” Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.
January 2024 in “Pediatric Dermatology” Minoxidil improved hair growth in a child with a rare genetic disorder.
11 citations
,
January 1985 in “British Journal of Dermatology” The document concludes that an inherited nail condition often improves on its own, and spironolactone effectively treats acne in women.
6 citations
,
January 2017 in “Dermato-endocrinology” ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.