April 2017 in “The Journal of urology/The journal of urology” 5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.
December 2025 in “Molecular Pain” Targeting the MC-5-HT-HTR2A axis may help treat chronic itching.
8 citations
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February 2013 in “Neuroscience Letters” Allopregnanolone may help prevent nicotine withdrawal symptoms.
42 citations
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May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
December 2021 in “Daehanhanuihakoeji” The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.
Neurosteroids help control dopamine responses in the brain.
10 citations
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March 2023 in “Journal of Chemistry” New compounds show promise for treating benign prostate hyperplasia with fewer side effects.
3 citations
,
March 2012 in “Arab Journal of Urology” Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.
83 citations
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January 2004 in “Pharmacology & Therapeutics” Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.
November 2023 in “JEADV Clinical Practice” Patients with severe alopecia areata felt better and less anxious or depressed when treated with baricitinib compared to placebo.
7 citations
,
October 2017 in “Behavioural Pharmacology” Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.
3 citations
,
May 2018 in “Psychiatry and Clinical Psychopharmacology” N-acetylcysteine may help treat trichotillomania.
2 citations
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January 2011 in “Andrologia” Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.
1 citations
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December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
August 1978 in “Dicp-The annals of pharmacotherapy” Crash diets can cause temporary hair loss, and professional medical advice can prevent serious health issues.
April 2023 in “Journal of Investigative Dermatology” Narrowband Ultraviolet B treatment can significantly reduce anxiety in psoriasis patients, but it doesn't significantly affect depression.
January 2024 in “Bratislavské lekárske listy/Bratislava medical journal” Chloroquine and cinchonine relax rat blood vessels by affecting calcium channels, with chloroquine needing caution in heart patients.
January 2025 in “Organics” Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
April 2017 in “European Psychiatry” Some antidepressants can cause emotional numbness and other unusual side effects.
20 citations
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November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.
December 2025 in “International Neurourology Journal” Alpha-blockers and 5-alpha reductase inhibitors don't significantly increase dementia risk.
40 citations
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December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
June 2026 in “The Journal of Sexual Medicine” Finasteride may be linked to more psychiatric issues than dutasteride, but a definite cause isn't proven.
52 citations
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October 2016 in “Clinics in Dermatology” Some medications can cause acne, and stopping these drugs is the main treatment.
47 citations
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January 2003 in “American Journal of Clinical Dermatology” Mood stabilizers can cause serious skin reactions; careful monitoring and immediate treatment are crucial.
19 citations
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October 2013 in “Headache: The Journal of Head and Face Pain” The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.
17 citations
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October 2012 in “European Journal of Pharmacology” Toluene lowers body temperature through different mechanisms depending on the concentration.
30 citations
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February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.