Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
21 citations
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September 1966 in “Toxicology and Applied Pharmacology” Caffeine becomes more toxic in rats when food intake is reduced by over 50%.
21 citations
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February 2003 in “Hormones and Behavior” Androgens boost certain nest-building behaviors and greatly reduce food intake in rabbits.
46 citations
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September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
2 citations
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January 2025 in “Сибирский научный медицинский журнал” TS-13 effectively stops tumor growth and reduces chemotherapy side effects.
12 citations
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July 1958 in “Journal of Endocrinology” Cortisone suppresses hair regrowth, especially undercoat hair, while adrenalectomy affects hair growth differently in rabbits and rats.
April 2018 in “Journal of Investigative Dermatology” The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
June 2025 in “Problems of Cryobiology and Cryomedicine” Low temperatures don't harm hyaluronic acid's healing abilities.
MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
164 citations
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December 1984 in “Proceedings of the National Academy of Sciences” TCDD reduces EGF receptor activity and causes various developmental changes in animals.
9 citations
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July 1961 in “Journal of Investigative Dermatology” Cutaneous calcinosis can be induced in young animals using certain compounds, but only in specific areas and with high mortality.
8 citations
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May 2020 in “Arthritis research & therapy” DHT inhibition may increase spinal bone growth in ankylosing spondylitis.
April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
1 citations
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January 1980 in “Acta Dermato Venereologica” Oral tetracycline reduces fat breakdown in hair lipids.
November 2024 in “Journal of Investigative Dermatology” Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
12 citations
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December 1965 in “Immunology and Cell Biology” Mild skin injury can trigger mineral deposits in rat skin, even without full calciphylactic response.
1 citations
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February 2014 in “Archiv Der Pharmazie” Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
51 citations
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June 1970 in “British journal of dermatology/British journal of dermatology, Supplement” Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
36 citations
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July 2005 in “Journal of Neuroendocrinology” Blocking certain brain processes reduces mating behavior in female rats.
37 citations
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January 2006 in “Carcinogenesis” Antizyme slows skin tumor growth by reducing cell growth in mice.
1 citations
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July 2022 in “Han'gug sigpum yeong'yang gwahag hoeji/Journal of the Korean society of food science and nutrition” Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.
December 2024 in “Quality in Sport” Hormonal balance is vital for women's health and performance, but therapies like contraceptives and steroids have both benefits and risks.
December 2019 in “theses.fr (ABES)” Lower TGFß1 levels help stem cells become beige fat cells.
April 2023 in “Journal of Investigative Dermatology” Tumescent liposuction reduces waist and hip size but doesn't significantly change metabolic markers, though it may slightly improve blood pressure and certain protein levels.
7 citations
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October 2010 in “Medical Hypotheses” Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
2 citations
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January 2025 in “动物学研究” YAP1 helps fat cell formation by influencing the Hippo pathway.
29 citations
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February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
December 2014 in “Annals of psychophysiology” Power-enhancing drugs can cause mood swings, aggression, anxiety, and physical side effects, questioning their overall benefits.
1 citations
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March 2018 in “F1000Research” Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.