Levetiracetam and valproate sodium both reduce seizures when added to lamotrigine, but levetiracetam has fewer side effects.
55 citations
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December 1983 in “Acta Neurologica Scandinavica” Carbamazepine, valproate, and clonazepam can cause mild to serious side effects during long-term epilepsy treatment.
Sodium valproate improved epilepsy control in most children but often caused weight gain and other mild side effects.
5 citations
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January 2017 in “Nevrologiâ, nejropsihiatriâ, psihosomatika” Sustained-release sodium valproate is effective in treating epilepsy, with some side effects influenced by genetics.
4 citations
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October 1993 in “PubMed” Valproic acid can cause mild side effects like anorexia and hair loss in some epileptic patients.
169 citations
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August 1981 in “BMJ” Sodium valproate improved epilepsy control but often caused weight gain in children.
73 citations
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January 1980 in “Annals of Neurology” Valproic acid can cause serious side effects, including pancreatitis and even death.
1 citations
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April 2002 in “PubMed” Anti-epileptic drugs may cause visual and hair side effects due to enzyme inhibition, especially in genetically predisposed individuals.
1 citations
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April 2015 in “Russkij žurnal detskoj nevrologii” Antiepileptic drugs can cause side effects like menstrual problems and infertility in women with epilepsy, but most pregnancies result in healthy babies, with newer drugs being safer.
16 citations
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February 2009 in “Clinical neurology and neurosurgery” Switching to extended-release divalproex sodium improved patient-reported tremor but did not change seizure frequency or most side effects.
10 citations
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October 2016 in “Epilepsy & behavior” Levetiracetam often causes behavioral issues, while oxcarbazepine is more likely to cause sleepiness in epilepsy patients.
January 2025 in “Seizure” Dual anti-seizure medications, especially valproic acid with lamotrigine, often cause more side effects like hair loss and memory issues.
18 citations
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January 2009 in “Acta neurologica Scandinavica” Long-term sodium valproate treatment for epilepsy generally caused mild and temporary side effects.
59 citations
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October 1976 in “Acta Neurologica Scandinavica” Sodium valproate reduced seizures in many patients with resistant epilepsy.
21 citations
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April 2011 in “Epilepsia” The drug combination significantly reduced epileptic drop attacks in patients.
1 citations
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December 1982 in “PubMed” Sodium valproate effectively reduces seizures in children with epilepsy, especially in primary generalized cases.
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April 2019 in “Russkij žurnal detskoj nevrologii” Some epilepsy drugs can cause reproductive and cosmetic side effects in women and affect pregnancy, but most women still have healthy babies.
November 2023 in “Children” Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.
November 2001 in “The Journal of neuropsychiatry and clinical neurosciences/The journal of neuropsychiatry and clinical neurosciences” Divalproex sodium can unexpectedly cause agitation and hyperactivity in some patients.
44 citations
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October 2016 in “Epilepsia” 2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
4 citations
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November 2001 in “Journal of Neuropsychiatry” Divalproex sodium can sometimes worsen behavior in some patients.
January 2004 in “Headache” Divalproex sodium significantly improved headaches in two-thirds of patients.
June 2021 in “Research Square (Research Square)” Sudanese epilepsy patients often experience hair loss from anti-epileptic drugs but continue their medication regardless of cosmetic side effects.
6 citations
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March 1986 in “PubMed” Valproic acid can cause weight gain and hair texture changes.
7 citations
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September 2007 Valproate sustained-release is effective and generally safe for short-term treatment of new partial epilepsy.
December 2006 in “The Brown University Psychopharmacology Update” Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
June 2023 in “International Journal of Pharmaceuticals Nutraceuticals and Cosmetic Science” New information shows Valproate may protect the brain and reduce breathing failure risk but can cause liver damage and other side effects, with genetics affecting dosage needs.
January 2025 in “Dusunen Adam The Journal of Psychiatry and Neurological Sciences”
January 2019 in “Pediatric Oncall” Sodium valproate can rarely cause curly hair in children.
January 2024 in “Specialty journal of Pharmacognosy Phytochemistry and Biotechnology” Genetic factors may influence how well valproic acid works and its side effects in epilepsy treatment.