4 citations
,
November 2001 in “Journal of Neuropsychiatry” Divalproex sodium can sometimes worsen behavior in some patients.
March 2018 in “New scientist” 4 citations
,
January 2019 in “PubMed” Low dose valproate in epileptic children mainly causes weight gain and other non-life-threatening side effects.
2 citations
,
January 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” Zinc supplements may help reduce hair loss caused by levetiracetam without affecting seizure control.
7 citations
,
September 2007 Valproate sustained-release is effective and generally safe for short-term treatment of new partial epilepsy.
May 2022 in “Indian Journal of Pharmacology” Sodium valproate can cause serious high blood pressure in children.
February 2009 in “Mayo Clinic proceedings” A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.
16 citations
,
May 2009 in “Journal of child neurology” Valproic acid does not change biotinidase enzyme activity in children's blood.
January 2019 in “Pediatric Oncall” Sodium valproate can rarely cause curly hair in children.
136 citations
,
January 2004 in “Neuroscience” Testosterone increases seizure risk through its conversion to specific neurosteroids.
1 citations
,
October 2019 in “Epileptic disorders” A girl with Pitt-Hopkins syndrome developed curly hair as a rare side effect from the epilepsy drug perampanel.
1 citations
,
December 2024 in “ACS Biomaterials Science & Engineering” The patches could quickly deliver epilepsy treatment and reduce seizures.
17 citations
,
January 2013 in “Indian Journal of Pharmacology” High levels of the seizure medication sodium valproate can cause hair loss.
January 2017 in “SHILAP Revista de lepidopterología” Agomelatine might help reduce hair loss caused by valproate.
January 2014 in “eScholarship (California Digital Library)” Targeting specific GABA receptors may help treat epilepsy and postpartum depression.
21 citations
,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
13 citations
,
February 2013 in “BMJ Case Reports” Stopping finasteride improved seizure control, suggesting neurosteroids affect seizures and treatment.
20 citations
,
January 2017 in “Epilepsia” Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
5 citations
,
January 2016 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause rare hair curling in some patients.
January 2024 in “Wiadomości Lekarskie” Effective epilepsy management involves accurate diagnosis, understanding seizure types, identifying causes, and choosing the right treatment.
5 citations
,
November 2012 in “Journal of Clinical Psychopharmacology” Valproic acid and isoniazid can interact, causing toxicity, so careful monitoring is needed.
12 citations
,
August 2006 in “American Journal of Psychiatry” Topiramate may help improve disruptive behaviors in children with bipolar disorder.
19 citations
,
June 2013 in “Journal of Neuroendocrinology” Neurosteroids may help prevent seizures and slow epilepsy progression.
16 citations
,
October 2004 in “Acta dermato-venereologica” Two people lost a lot of hair because of epilepsy drugs, but their hair grew back after changing medication.
2 citations
,
July 2018 in “Journal of pediatric epilepsy” A teenager lost hair after starting epilepsy medication levetiracetam.
May 2011 in “Psychiatric News” Horizant has risks like other seizure drugs, Johnson & Johnson misled about Risperdal, and Quanterix found a possible link between brain oxygen loss and Alzheimer's markers.
2 citations
,
April 2023 in “Curēus” Valproic acid can cause muscle damage and liver issues, which improve after stopping the drug.
2 citations
,
August 2002 in “British Journal of Ophthalmology” Tangent screens help detect visual field defects from vigabatrin.
November 2022 in “Indian Journal of Dermatology/Indian journal of dermatology” Valproic acid can cause dark lines on nails.