88 citations
,
October 2002 in “Journal of Dermatology” Finasteride for hair loss may cause depression, affecting sleep and relationships.
August 2017 in “Drug and Therapeutics Bulletin” Finasteride may cause depression, suicidal thoughts, and sexual side effects.
January 2013 in “Psychiatry and clinical neurosciences” Physical symptoms in depression can reveal underlying medical conditions.
August 2025 in “medRxiv (Cold Spring Harbor Laboratory)” 5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.
8 citations
,
November 2011 in “Journal of Medical Case Reports” Bupropion may help treat trichotillomania when fluoxetine doesn't work.
January 2026 in “Cronfa (Swansea University)” Finasteride and dutasteride may increase the risk of depression and suicidality, so patients should be monitored closely.
January 2007 in “UNIFESP Institutional Repository (Universidade Federal de São Paulo)” Addressing anxiety and mood disorders is crucial to reduce medication overuse in chronic migraine patients.
2 citations
,
October 2002 in “American Journal of Nursing” Taking the same medication under different brand names caused harmful side effects.
June 2025 in “Reactions Weekly” Finasteride may increase the risk of depression and suicidal thoughts.
October 2025 in “Reactions Weekly”
April 2020 in “Online journal of complementary & alternative medicine” Some medications can help increase sexual desire and function in women.
January 2024 in “Wiadomości Lekarskie” New methods are improving treatment for depression.
9 citations
,
January 2009 in “PubMed” Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
February 2026 in “Postgraduate Medicine” 5-alpha reductase inhibitors slightly increase depression risk, but the risk varies based on the control group used.
July 2017 in “Clin-Alert” Different medications can cause serious side effects in some people.
110 citations
,
August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
Certain medications, especially 5-alpha reductase inhibitors, are commonly linked to erectile dysfunction.
August 2012 in “Reactions Weekly” Finasteride users with sexual issues often experience depression.
1 citations
,
August 2017 in “The Journal of urology/The journal of urology” 5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.
July 2024 in “Behavioural Brain Research” Long-term finasteride treatment reduces depression and brain issues in obese male rats.
2 citations
,
September 2009 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
9 citations
,
April 2020 in “The Journal of Urology” 5α-Reductase inhibitors don't cause depression.
April 2026 in “The Journal of Steroid Biochemistry and Molecular Biology”
November 2003 in “Journal of Dermatology” Finasteride's link to depression is questionable due to study flaws and potential bias.
2 citations
,
June 2022 in “INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)” Vitamin D can help reduce depression in people with hypothyroidism.
October 2025 in “Reactions Weekly” Finasteride and dutasteride may cause depression and suicidal thoughts.
April 2026 in “Brain Sciences” Finasteride may cause depression and suicidal thoughts, especially in young men.
2 citations
,
March 2016 in “Düşünen Adam” Switching from escitalopram to duloxetine improved hair loss.
December 2025 in “The Journal of Clinical Psychiatry” Finasteride can cause depression and suicidal thoughts; safer alternatives are recommended.
8 citations
,
January 2016 in “Case Reports in Psychiatry” Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.