February 2024 in “Journal of Education, Health and Sport” Some skin medication can rarely cause or worsen mental health issues; knowing this is important because mental health problems are increasing worldwide.
June 2017 in “Reactions Weekly” Finasteride (Propecia) may cause depression and suicidal thoughts; stop use and inform a healthcare professional if symptoms develop.
1 citations
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June 2025 in “European Journal of Clinical Pharmacology” Finasteride may increase the risk of suicidality and depression, especially in younger people.
December 2023 in “Magna Scientia Advanced Research and Reviews” The document suggests using trazodone and clomiphene to treat sexual dysfunction caused by post-finasteride syndrome.
1 citations
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November 2022 in “INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)” Vitamin D helps reduce depression in people with autoimmune thyroiditis and hypothyroidism.
June 2026 in “The Journal of Sexual Medicine” Finasteride may be linked to more psychiatric issues than dutasteride, but a definite cause isn't proven.
May 2024 in “European urology focus” Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
4 citations
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July 2021 in “Journal of Dermatological Treatment” Finasteride helps hair growth but may cause sexual side effects and depression.
June 2024 in “Drug and therapeutics bulletin” Finasteride can cause depression, suicidal thoughts, and lasting psychiatric and sexual issues.
December 2006 in “The Brown University Psychopharmacology Update” Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
May 2025 in “Psychopharmacology” Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.
10 citations
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December 2014 in “PubMed” Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.
July 2009 in “Guoji yiyao weisheng daobao” Combining α1A-blockers with Prozac is more effective for treating premature ejaculation than Prozac alone.
Men with sexual side effects from finasteride may face higher risks of depression and suicidal thoughts.
27 citations
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April 2008 in “Neuroscience Letters” Olanzapine reduces stress-related anxiety in rats when given acutely.
July 2024 in “jurnal ABDIMAS Indonesia” Early detection of apolipoprotein levels helps reduce depression risk in the elderly.
2 citations
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July 2019 in “Digital Showcase Research, Scholarship, & Creative Works (University of Lynchburg)” No proven link between isotretinoin and depression.
February 2024 in “Urology” Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
May 2017 in “Psychiatric news” BPH medications may increase the risk of self-harm and depression, especially in the first 18 months.
January 2012 in “The Journal of Clinical Psychiatry”
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
February 2026 in “Cureus” Testosterone therapy had limited benefits for a man with depression and suspected low testosterone, highlighting the need for careful diagnosis and treatment planning.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.
September 2025 in “The Journal of Clinical Psychiatry” Finasteride may increase depression and suicide risks, needing better safety checks and informed consent.
1 citations
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March 2020 in “Journal of Pharmacological Sciences” Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.
September 2025 in “Therapies” Finasteride use for hair loss may cause depression and suicidal thoughts, requiring careful monitoring.
December 2025 in “The Journal of Clinical Psychiatry” Finasteride is not proven to cause depression or suicide, and careful patient monitoring is advised.
May 2024 in “Psychiatric News” Weight-loss drugs are not linked to suicidal thoughts.
November 2003 in “Journal of Dermatology” Authors defend finasteride-depression link, suggest detailed medical history, and call for more investigation.