September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Finasteride may help reduce opioid use.
May 2017 in “Psychiatric news” BPH medications may increase the risk of self-harm and depression, especially in the first 18 months.
April 2009 in “Journal of Pain” Finasteride reduces pain in male rats and works better with testosterone.
134 citations
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August 2012 in “The Journal of Clinical Psychiatry” Former finasteride users with persistent sexual side effects have higher rates of depression and suicidal thoughts.
April 2016 in “Journal of The American Academy of Dermatology” Finasteride and SSRIs together increase impotence and low libido risk in men.
December 2025 in “Instituto Politécnico do Porto” Patients with mood disorders using 5α-reductase inhibitors may have a higher risk of suicidal thoughts.
4 citations
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November 2001 in “Journal of Neuropsychiatry” Divalproex sodium can sometimes worsen behavior in some patients.
September 2021 in “Journal of skin and stem cell” Lactium, a milk protein, can help reduce symptoms of skin disorders linked to stress and anxiety without side effects.
January 2013 in “Yearbook of Urology” Former finasteride users showed higher rates of depression and suicidal thoughts compared to those who never used it.
May 2024 in “News Digital Object Group” 64 citations
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March 2008 in “Neuropsychopharmacology” 111 citations
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August 2015 in “Reviews in Endocrine and Metabolic Disorders” 5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.
8 citations
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January 2016 in “Case Reports in Psychiatry” Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.
8 citations
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April 2021 in “Journal of Clinical Investigation” Finasteride reduces opioid use and withdrawal symptoms in animals.
1 citations
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April 2019 in “The Journal of urology/The journal of urology” Marijuana use is linked to higher chances of needing treatment for urinary symptoms in men over 40.
January 2022 in “Drugs of Today” 66 citations
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January 2008 in “Pharmacology Biochemistry and Behavior” AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
April 2026 in “Frontiers in Pharmacology” Many medications may be linked to cognitive disorders, but most lack warnings on labels.
January 2025 in “The Atlantic Journal of Medical Science and Research” Many dermatology patients experience anxiety and depression, especially those with acne or psoriasis.
May 2024 in “Reactions weekly” September 2025 in “Frontiers in Pharmacology” Platycladus Orientalis leaf vesicles may help treat anxiety, depression, and insomnia.
May 2024 in “Psychiatric News” Weight-loss drugs are not linked to suicidal thoughts.
February 2024 in “Journal of Education, Health and Sport” Some skin medication can rarely cause or worsen mental health issues; knowing this is important because mental health problems are increasing worldwide.
January 2011 in “Reactions Weekly” Lower adiponectin levels may relate to depression in women with PCOS.
11 citations
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September 2008 in “European Journal of Drug Metabolism and Pharmacokinetics” Finasteride helps reduce pain and inflammation in animals.
52 citations
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April 2002 in “Brain Research” Lower allopregnanolone levels increase stress-related dopamine release in the brain.