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20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Estrogen may help improve COVID-19 outcomes, especially in women.

Testosterone affects vascular cells directly without converting to estradiol.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

A rare, non-cancerous ovarian tumor was successfully treated with surgery, improving the patient's symptoms.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Spironolactone may help reduce hair growth and testosterone levels in some women with hirsutism.

Anabolic-androgenic steroids harm male hormone levels, sperm, metabolism, and can cause acne, hair loss, and breast growth.

Clomiphene testing can help find ovarian causes of high testosterone in postmenopausal women.

ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.

Spironolactone might cause painful intercourse and decreased sexual arousal in women.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Flutamide helps with prostate cancer and some skin conditions but can harm the liver.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Testosterone therapy can safely and effectively treat symptoms like low libido and fatigue in women, especially after menopause.

Alfatradiol (0.025%) is an effective and safe treatment for hair loss in both women and men.

The document concludes that doctors should thoroughly check postmenopausal women with sudden increased male traits for rare conditions like androgen-producing endometrial cancer.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.