24 citations
,
October 2016 in “Oncotarget” Finasteride has a higher risk of reproductive side effects than minoxidil.
February 2026 in “European Urology” Finasteride may cause depression and affect brain and gut health in male rats.
July 2015 in “Pharmacological Reports” Finasteride weakens the bone-protective effects of certain blockers in low androgen conditions.
6 citations
,
April 2009 in “Fertility and Sterility” Finasteride helps induce ovulation in nonresponder PCOS women.
108 citations
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January 2010 in “International Journal of Andrology” Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.
18 citations
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January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
67 citations
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February 1997 in “Teratology” Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.
15 citations
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July 2019 in “Journal of Biological Inorganic Chemistry” Finasteride helps prevent kidney stones, but side effects need more research.
195 citations
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February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
November 1998 in “Hair transplant forum international” Finasteride is considered to have a low risk to fetuses.
1 citations
,
January 2010 in “uO Research (University of Ottawa)” Atrazine and finasteride disrupt hormone signaling and affect frog development.
May 2015 in “Journal of The American Academy of Dermatology” Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.
5 citations
,
January 2020 in “in Vivo” Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
86 citations
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March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
5 citations
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October 2012 in “Journal of Midwifery & Women's Health” Healthcare providers should start with simple fertility tests and treatments before referring patients to specialists.
21 citations
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September 1994 in “The Journal of Clinical Endocrinology and Metabolism”
24 citations
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December 2013 in “Sexual medicine reviews” Finasteride can cause sexual problems and depression in young men.
1 citations
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January 2012
January 2021 in “Journal of Shaheed Suhrawardy Medical College” Cyproterone acetate and ethinylestradiol significantly lowered AMH levels in PCOS patients resistant to clomiphene.
2 citations
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October 2000 in “The Journal of Urology” Finasteride daily doesn't affect sperm production or semen in young men.
2 citations
,
July 2021 in “Journal of Dermatology and Dermatologic Surgery” Exposure to the hair loss drug finasteride during pregnancy can cause genital anomalies in male babies, but not in female babies. It's best to avoid this drug in women who could potentially become pregnant.
3 citations
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April 1977 in “PubMed” The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.
23 citations
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October 2015 in “Andrology” New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
26 citations
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November 2006 in “Pharmacology, Biochemistry and Behavior” Pregnancy reduces anxiety in rats, but finasteride reverses this effect.
March 2024 in “The journal of sexual medicine” Finasteride's negative effects on brain tissue in male rats may be reversible after stopping the drug.
2 citations
,
March 2017 in “Canadian Urological Association journal” Clomiphene citrate improves fertility in men taking finasteride for hair loss.
Finasteride reduces blood vessel formation in seminal vesicles.
13 citations
,
June 2018 in “Current Urology Reports” Hair loss drugs may cause sexual issues and infertility in men.