67 citations
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February 2015 in “Life Sciences” Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.
54 citations
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January 2018 in “Scientific reports” Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
47 citations
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May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
45 citations
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July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
42 citations
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August 1999 in “The American journal of pathology” Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
40 citations
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June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” FA2H is essential for normal fur and sebum production in mice.
39 citations
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August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
35 citations
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May 2020 in “Frontiers in Pharmacology” Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
35 citations
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July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
34 citations
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July 2009 in “Journal of Cell Science” ΔNp63α helps control a protein that stops cancer cells from spreading.
31 citations
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April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
30 citations
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July 2019 in “PloS one” Patients with Alopecia areata have fewer specific immune cells that normally regulate the immune system, which may contribute to the condition.
30 citations
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November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
26 citations
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July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
25 citations
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August 2010 in “Journal of Biological Chemistry” Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
23 citations
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May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
18 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
18 citations
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November 2014 in “Journal of Agricultural and Food Chemistry” Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.
13 citations
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September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
12 citations
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December 2017 in “Food and chemical toxicology” Permanent hair dye mixtures can irritate and damage the skin.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
11 citations
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February 2018 in “Amino acids” Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
9 citations
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January 2023 in “Cellular and Molecular Life Sciences” Botulinum toxin A can help improve thin endometrium and embryo implantation.
9 citations
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April 2019 in “Molecules” Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
9 citations
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January 2019 in “American Journal of Dermatopathology” DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.
8 citations
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February 2019 in “Scientific Reports” Immunofluorescence tomography is a cost-effective method for creating detailed 3-D images of tissues.
8 citations
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September 2002 in “Genes to Cells” Killing specific cells in hair follicles can lead to hair growth problems in mice.
6 citations
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January 2021 in “International Journal of Molecular Sciences” Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
5 citations
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August 2025 in “Drug Delivery and Translational Research” Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.