research Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication
Laminin α5 is essential for skin communication and health.
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research Interleukin-15 is a hair follicle immune privilege guardian
Interleukin-15 can help hair growth and protect hair follicles.
research Role of the SOX family in cancer immune evasion: Emerging player and promising therapeutic opportunities
Targeting SOX proteins may improve cancer treatment by restoring immune function.
research Research Progress of Extracellular Vesicles-Loaded Microneedle Technology
Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
research Dutasteride: a review of current data on a novel dual inhibitor of 5alpha reductase.
Dutasteride effectively treats enlarged prostate with manageable side effects.
research Long-Term Experience With 5-alpha-Reductase Inhibitors.
Finasteride reduces prostate size and symptoms with few side effects.
research Molecular stratification of the human fetal vaginal epithelium by spatial transcriptome analysis
The study identifies four distinct zones in the fetal vaginal epithelium, enhancing understanding for potential applications in women's health.
research Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles
S100A8 and S100A9 proteins help form hair shafts during growth.
research Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications
Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.
research Pollen Allergies in Humans and their Dogs, Cats and Horses: Differences and Similarities
Humans and pets share similar allergy mechanisms, and studying pet allergies can help treat both human and animal allergies.
research Visible-to-Near IR Quantum Dot–Based Hypermulticolor High-Content Screening of Herbal Medicines for the Efficacy Monitoring of Hair Growth Promotion and Hair Loss Inhibition
Some herbal extracts can promote hair growth and prevent hair loss.
research The Possible Role of Antibodies in Alopecia: A Narrative Review
The role of antibodies in alopecia is unclear, but JAK inhibitors show promise for treatment.
research The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
Females generally have stronger immune responses than males due to the X chromosome.
research Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair
NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.
research An Overview of Biopolymeric Electrospun Nanofibers Based on Polysaccharides for Wound Healing Management
Polysaccharide-based nanofibers are promising for better wound healing.
research Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK / STAT1 signaling pathway
JAK/STAT1 pathway causes hair loss during chemotherapy by reducing Shh in hair follicles.
research Protective Effects of a New Human Placental Extract Against Hair Graying and Chemotherapy-Induced Peripheral Neuropathy
The new human placental extract may help prevent hair graying and reduce nerve pain from chemotherapy.
research Do nanoparticles have a future in dermal drug delivery?
Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.
research Genetic Variants and Protective Immunity against SARS-CoV-2
Genetic differences affect how people respond to COVID-19.
research Dynamic immunomodulatory nanoarchitectonics: Rewiring tissue regenerative microenvironment via intelligent regulation
Nanotechnology can improve tissue healing by controlling immune responses.
research ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on fetal guinea pig brain development.
Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.
research Quercetin and polycystic ovary syndrome
Quercetin may help improve symptoms of polycystic ovary syndrome.
research Multimodal roles of transient receptor potential channel activation in inducing pathological tissue scarification
Targeting TRP channels may help reduce excessive scarring.
research Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium
COVID-19 may cause hair loss by affecting hair follicles.
research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
research Towards a consensus potency assay for mesenchymal stromal cells: a matrix analysis of cell source, donor variability and inflammatory stimuli to refine surrogate markers of immunomodulation
ATIR101 improves survival in stem cell transplant patients; Australian stem cell treatment decisions are influenced by regulation changes.
research iNKT cells ameliorate human autoimmunity: Lessons from alopecia areata
iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.