research The impact of oxidative stress on hair
Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.
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research Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
research How to diagnose a lipodystrophy syndrome
The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
research Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Skin fat plays a key role in immune defense and healing beyond just storing energy.
research Hair follicles, their disorders and their opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
FA2H is essential for normal fur and sebum production in mice.
research Current management strategies for cutaneous T-cell lymphoma
The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia
The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
research Deciphering the functions of the hair follicle infundibulum in skin physiology and disease
The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
research Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids
Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
research Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
research Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease
Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
research Skin disease in pregnancy
Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.
research Straight hair associated with interferon-alfa plus ribavirin in hepatitis C infection
ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
research The Clinical Presentation of Systemic Lupus Erythematosus
Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
research Proliferative and necrotizing otitis externa in four cats
Topical 0.1% tacrolimus significantly improved ear infections in cats.
research Transformation of amnion epithelium into skin and hair follicles
Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
research Organ Specificity in Autoimmune Diseases: Thyroid and Islet Autoimmunity in Alopecia Areata
Alopecia areata is linked to thyroid autoimmunity but not type 1 diabetes.
research LPA3, a unique G protein-coupled receptor for lysophosphatidic acid
LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
research Carriers of 21-Hydroxylase Deficiency Are Not at Increased Risk for Hyperandrogenism*
People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.
research Fibrosing alopecia in a pattern distribution
Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
research Dormancy in the stem cell niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research Clinical Significance of Dense Fine Speckled Pattern in Anti-nuclear Antibody Test using Indirect Immunofluorescence Method
The dense fine speckled pattern in ANA tests is common in autoimmune diseases, challenging previous beliefs that it was unrelated.
research MicroRNA in skin diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.