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The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

The assay effectively detects hormonal activity of certain chemicals.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Adiantum capillus extract reduces pain and swelling in animals.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.

The compound 4c showed strong potential as an anticancer agent.

3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.

Combining a GnRH agonist with a low-dose oral contraceptive is more effective and safer for treating hirsutism than using either alone.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

New progesterone-based compounds can block male hormones.

The retinoid receptor antagonist effectively disrupts vitamin A-related development in embryos.

Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

Certain drugs can cause early hair growth in mice by affecting the nerves.